Herpes simplex virus and varicella zoster virus, the house guests who never leave.

Herpesviridae Pub Date : 2012-06-12 DOI:10.1186/2042-4280-3-5

Paul R Kinchington, Anthony J St Leger, Jean-Marc G Guedon, Robert L Hendricks

引用次数: 92

Abstract

Human alphaherpesviruses including herpes simplex viruses (HSV-1, HSV-2) and varicella zoster virus (VZV) establish persistent latent infection in sensory neurons for the life of the host. All three viruses have the potential to reactivate causing recurrent disease. Regardless of the homology between the different virus strains, the three viruses are characterized by varying pathologies. This review will highlight the differences in infection pattern, immune response, and pathogenesis associated with HSV-1 and VZV.

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单纯疱疹病毒和水痘带状疱疹病毒，是家里永远不会离开的客人。

人类甲型疱疹病毒包括单纯疱疹病毒(HSV-1、HSV-2)和水痘带状疱疹病毒(VZV)在宿主的感觉神经元中建立持续潜伏感染。这三种病毒都有可能重新激活，导致疾病复发。不考虑不同病毒株之间的同源性，这三种病毒的特点是不同的病理。本文将重点介绍HSV-1和VZV在感染模式、免疫反应和发病机制方面的差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Herpesviridae

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