Two new aliphatic lactones from the fruits of Coriandrum sativum L.

Organic and Medicinal Chemistry Letters Pub Date : 2012-07-16 DOI:10.1186/2191-2858-2-28

Kamran J Naquvi, Mohammed Ali, Javed Ahmad

{"title":"Two new aliphatic lactones from the fruits of Coriandrum sativum L.","authors":"Kamran J Naquvi, Mohammed Ali, Javed Ahmad","doi":"10.1186/2191-2858-2-28","DOIUrl":null,"url":null,"abstract":"Background: The present paper describes the isolation and characterization of two new aliphatic δ-lactones along with three glycerides and n-nonadecanyl cetoleate from the fruits of Coriandrum sativum L. (Apiaceae). The structures of all the isolated phytoconstituents have been established on the basis of spectral data analysis and chemical reactions.Results: Phytochemical investigation of the methanolic extract of C. sativum L. (Apiaceae) fruits resulted in the isolation of two new aliphatic δ-lactones characterized as 2α-n-heptatriacont-(Z)-3-en-1,5-olide (1) (coriander lactone) and 2α-n-tetracont-(Z,Z)-3,26-dien-18α-ol-1,5-olide (2) (hydroxy coriander lactone) together with glyceryl-1,2-dioctadec-9,12-dienoate-3-octadec-9-enoate (3); glyceryl-1,2,3-trioctadecanoate (4); n-nonadecanyl-n-docos-11-enoate (5) and oleiyl glucoside (6).Conclusions: Phytochemical investigation of the methanolic extract of C. sativum gave coriander lactone and hydroxy coriander lactone as the new phytoconstituents.","PeriodicalId":19639,"journal":{"name":"Organic and Medicinal Chemistry Letters","volume":"2 1","pages":"28"},"PeriodicalIF":0.0000,"publicationDate":"2012-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/2191-2858-2-28","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic and Medicinal Chemistry Letters","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/2191-2858-2-28","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 5

Abstract

Background: The present paper describes the isolation and characterization of two new aliphatic δ-lactones along with three glycerides and n-nonadecanyl cetoleate from the fruits of Coriandrum sativum L. (Apiaceae). The structures of all the isolated phytoconstituents have been established on the basis of spectral data analysis and chemical reactions.

Results: Phytochemical investigation of the methanolic extract of C. sativum L. (Apiaceae) fruits resulted in the isolation of two new aliphatic δ-lactones characterized as 2α-n-heptatriacont-(Z)-3-en-1,5-olide (1) (coriander lactone) and 2α-n-tetracont-(Z,Z)-3,26-dien-18α-ol-1,5-olide (2) (hydroxy coriander lactone) together with glyceryl-1,2-dioctadec-9,12-dienoate-3-octadec-9-enoate (3); glyceryl-1,2,3-trioctadecanoate (4); n-nonadecanyl-n-docos-11-enoate (5) and oleiyl glucoside (6).

Conclusions: Phytochemical investigation of the methanolic extract of C. sativum gave coriander lactone and hydroxy coriander lactone as the new phytoconstituents.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

芫荽果实中两个新的脂肪内酯。

背景:本文报道了从芫荽(Apiaceae)果实中分离和鉴定的两种新的脂肪族δ-内酯、三种甘油酯和鲸油酸n-壬烷醇。根据光谱数据分析和化学反应，确定了所有分离得到的植物成分的结构。结果:对樟科植物果实甲醇提取物进行植物化学分析，分离到2α-n-庚-(Z)-3-烯-1,5-烯内酯(1)(香菜内酯)和2α-n-四元-(Z,Z)-3,26-二烯-18α-醇-1,5-烯内酯(2)(羟基香菜内酯)和甘油-1,2-二癸-9,12-二烯-3-十八烯-9-烯酸酯(3)两个新的脂肪族δ-内酯;glyceryl-1 2 3-trioctadecanoate (4);结论:对芫荽醇提物的植物化学研究表明，芫荽内酯和羟基芫荽内酯是新的植物成分。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Organic and Medicinal Chemistry Letters

自引率

0.00%

发文量