Biomarker Discovery of Pancreatic and Gastrointestinal Cancer by 2DICAL: 2-Dimensional Image-Converted Analysis of Liquid Chromatography and Mass Spectrometry.

International journal of proteomics Pub Date : 2012-01-01 Epub Date: 2012-07-10 DOI:10.1155/2012/897412
Masaya Ono, Masahiro Kamita, Yusuke Murakoshi, Junichi Matsubara, Kazufumi Honda, Banno Miho, Tomohiro Sakuma, Tesshi Yamada
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引用次数: 13

Abstract

Biomarkers tested by blood sample are of great use to clinicians as they provide useful information to aid an early and accurate diagnosis. Comprehensive "omics" studies are expected to facilitate the identification of such new biomarkers, and much research is being performed in this area. Our proteomics analysis system of 2-dimensional image-converted analysis of liquid chromatography and mass spectrometry (2DICAL) has successfully identified several new blood biomarkers from the clinical blood samples of pancreatic and colorectal cancer patients.

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通过2dic发现胰腺癌和胃肠道癌症的生物标志物:液相色谱和质谱的二维图像转换分析。
血液样本检测的生物标志物对临床医生非常有用,因为它们提供了有用的信息,有助于早期准确诊断。全面的“组学”研究有望促进这些新的生物标志物的鉴定,并且在这一领域正在进行大量研究。我们的二维图像转换液相色谱和质谱分析(2dic)蛋白质组学分析系统已成功地从胰腺癌和结直肠癌患者的临床血液样本中鉴定出几种新的血液生物标志物。
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