An evidence-based medical visit for patients with rheumatoid arthritis based on standard, quantitative scientific data from a patient MDHAQ and physician report.

Theodore Pincus, Isabel Castrejón
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Abstract

An evidence-based visit is described based on quantitative, standard scientific data on two simple forms for a patient and a physician. The focus is rheumatoid arthritis (RA), but the principles may be applied to most rheumatic and chronic diseases. A quantitative patient history is recorded on a selfreport multidimensional health assessment questionnaire (MDHAQ), which includes scales for physical function, pain, patient global estimate, psychological distress, change in status, exercise status, morning stiffness, fatigue, and a template to score RAPID3 (routine assessment of patient index data 3). RAPID3, an index of only patient self-report measures, distinguishes active from control treatments in clinical trials at similar levels to a disease activity score (DAS28) and clinical disease activity index (CDAI) but is calculated in 5 seconds, compared to almost 2 minutes for DAS28 or CDAI. The MDHAQ also includes traditional "medical" matters-a self-report joint count, review of systems, recent medical history, medications, demographic data, and consents for future monitoring by mail and sharing data with research colleagues; these queries enhance acceptance by patients and save time for doctors. Patient questionnaire physical function scores-not radiographs or laboratory tests-are the most significant prognostic markers for long-term work disability and premature death in RA. The physician completes a "doctor evaluation" (DOCEVAL) form, which includes four visual analog scales for overall status, inflammation, damage, and "neither" (usually fibromyalgia), reflecting quantitatively the expertise of a rheumatologist to classify the etiology of pain and distress into one of these three broad categories in formulating a treatment plan. Quantitative data from patients and doctors on an evidence-based visit can advance rheumatology clinical care and clinical science.

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基于患者MDHAQ和医生报告的标准定量科学数据,为类风湿关节炎患者进行循证医疗访问。
以证据为基础的访问是基于定量的、标准的科学数据,以两种简单的形式对患者和医生进行描述。重点是类风湿关节炎(RA),但原则可能适用于大多数风湿性和慢性疾病。定量的患者病史记录在自我报告多维健康评估问卷(MDHAQ)上,其中包括身体功能、疼痛、患者总体估计、心理困扰、状态变化、运动状态、晨僵、疲劳的量表,以及RAPID3评分模板(患者指数数据常规评估3)。RAPID3是仅用于患者自我报告测量的指标。在疾病活动性评分(DAS28)和临床疾病活动性指数(CDAI)水平相似的临床试验中,将积极治疗与对照治疗区分开来,但在5秒内计算,而DAS28或CDAI几乎需要2分钟。MDHAQ还包括传统的“医疗”事项——自我报告、联合计数、系统回顾、近期病史、药物、人口统计数据,以及同意通过邮件进行未来监测和与研究同事共享数据;这些问题提高了患者的接受度,节省了医生的时间。患者问卷身体功能评分——而不是x光片或实验室检查——是类风湿关节炎患者长期工作残疾和过早死亡的最重要的预后指标。医生完成“医生评估”(DOCEVAL)表格,其中包括四种视觉模拟量表,包括总体状态、炎症、损伤和“两者都没有”(通常是纤维肌痛),定量反映风湿病学家在制定治疗计划时将疼痛和痛苦的病因分类为这三大类之一的专业知识。来自患者和医生的基于证据的访问的定量数据可以推进风湿病临床护理和临床科学。
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