Effectiveness of glycyrrhizinic Acid (glizigen) and an immunostimulant (viusid) to treat anogenital warts.

ISRN Dermatology Pub Date : 2012-01-01 Epub Date: 2012-08-14 DOI:10.5402/2012/863692
José Domínguez Gómez, Ramón Daniel Simón, Alfredo Abreu Daniel, Hana Zelenkova
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引用次数: 12

Abstract

Genital warts are benign proliferations of skin and mucosa caused by the human papillomavirus infection (hereinafter referred to as HPV). It is one of the most common sexually transmitted diseases in the world, whose incidence rate has increased in the last three decades. Current treatment involves the physical destruction of the infected cells. The fact that there are many different types of treatment goes to show that none of them are uniformly effective or directly antiviral. Objective. Demonstrate the efficacy of Glizigen in the III-phase clinical trial combined with a food supplement (VIUSID) formulated to boost the immune system when treating external anogenital warts. Design. 100 patients clinically diagnosed with anogenital lesions were included in the trial and assigned to two groups of 50 individuals. Those from one group where treated with Glizigen and Viusid and those from the other group with 25% podophyllin in alcohol, the results from each were then compared. Results. The combined Glizigen-Viusid treatment was seen to have an 87.5% efficacy rate, which was slightly more than that of the treatment with podophyllin, and there were hardly any adverse reactions reported during the treatment. Conclusions. the combined Glizigen-Viusid treatment was effective in treating genital warts.

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甘草酸(glizigen)和免疫刺激剂(病毒)治疗肛门生殖器疣的有效性。
生殖器疣是由人乳头瘤病毒(以下简称HPV)感染引起的皮肤和粘膜的良性增生。它是世界上最常见的性传播疾病之一,其发病率在过去三十年中有所增加。目前的治疗方法包括对感染细胞进行物理破坏。事实上,有许多不同类型的治疗方法表明,没有一种是统一有效或直接抗病毒的。目标。在iii期临床试验中证明Glizigen与一种食品补充剂(VIUSID)联合治疗外生殖器疣时增强免疫系统的功效。设计:100名临床诊断为肛门生殖器病变的患者被纳入试验,并被分为两组,每组50人。一组用Glizigen和Viusid治疗,另一组用25%的鬼紫素酒精治疗,然后比较两组的结果。结果。Glizigen-Viusid联合治疗有效率为87.5%,略高于podophilin治疗,且治疗过程中几乎未见不良反应报告。结论。Glizigen-Viusid联合治疗生殖器疣效果显著。
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