Characterization of bangerter filter effect in mild and moderate amblyopia associated with strabismus.

Carlos Laria, David P Pinero
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Abstract

Background: To evaluate the outcome achieved by using Bangerter filters in cases of mild to moderate amblyopia associated to strabismus.

Methods: Prospective study comprising 30 children (age range 2-9 years) with unilateral mild to moderate amblyopia associated to esotropia and hyperopia. All patients were treated by prescribing the use of a Bangerter filter in the non-amblyopic eye in combination with the refractive correction. In all cases, the filter selected induced a reduction of the visual acuity of 2 lines below the best spectacle-corrected visual acuity (BSCVA) of the amblyopic eye. A follow-up of 12 months was completed.

Results: A statistically significant improvement in BSCVA was observed at 3 months in amblyopic eyes (p 0.01), with additional significant improvements at 6, 9 and 12 months (p 0.02). The BSCVA in non-amblyopic eyes remained unchanged during the initial 6 months of treatment (p 0.52), with a significant improvement at 9 months (p=0.03). Significant differences between amblyopic and fellow eyes were only detected at 3 months (p 0.01). Filter density had to be changed during the follow-up in 12 eyes (40%). Inverse significant correlations between baseline filter density and BSCVA were found at the end of the follow-up (r -0.35, p 0.01). A significant correlation of the visual acuity with the baseline visual acuity difference among eyes was only present at 3 months (r=-0.55, p 0.01).

Conclusions: Bangerter filters seem to be useful for treating mild or moderate amblyopia due to strabismus, but ocular dominance inversion should be maintained during treatment for obtaining an optimized outcome.

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轻度和中度弱视伴斜视的巴格特滤光器效应的表征。
背景:评价使用Bangerter滤光片治疗轻度至中度弱视合并斜视的效果。方法:前瞻性研究包括30名儿童(年龄范围2-9岁)单侧轻度至中度弱视合并内斜视和远视。所有患者均在非弱视眼中使用Bangerter滤光片并结合屈光矫正。在所有病例中,所选择的滤光片使弱视眼的视力比最佳眼镜矫正视力(BSCVA)降低2线。随访12个月。结果:弱视患者在3个月时BSCVA有显著改善(p < 0.01),在6、9和12个月时有显著改善(p < 0.02)。非弱视眼的BSCVA在治疗前6个月保持不变(p 0.52),在治疗后9个月有显著改善(p=0.03)。弱视仅在3个月时与其他眼有显著性差异(p < 0.01)。随访期间,有12只眼(40%)需要更换滤光片密度。在随访结束时,基线滤过器密度与BSCVA呈显著负相关(r -0.35, p 0.01)。视力与眼间基线视力差异仅在3个月时存在显著相关性(r=-0.55, p 0.01)。结论:Bangerter滤光片治疗轻、中度斜视是有效的,但在治疗过程中应保持眼优势反转以获得最佳效果。
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