Bovine colostrum and immune function after exercise.

Medicine and sport science Pub Date : 2012-01-01 Epub Date: 2012-10-15 DOI:10.1159/000341966
Glen Davison
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引用次数: 30

Abstract

Strenuous and/or prolonged exercise causes transient perturbations in immune function. It is well accepted that this is one mechanism contributing to the higher occurrence of infection (e.g. upper respiratory tract infection (URTI)) in athletes, especially endurance athletes. URTI or upper respiratory tract (URT) symptoms can negatively affect training and competition performance but athletes must train intensively to be successful. Therefore, interventions that can legitimately enhance immune function and reduce URTI risk can be of benefit to athletes. Bovine colostrum supplementation has been investigated as a possible nutritional countermeasure to enhance (or maintain) immune function, and reduce URTI risk, following strenuous or prolonged exercise and during intensive training periods. There is convincing evidence that daily supplementation with bovine colostrum, for a number of weeks (and preliminary evidence for acute effects after a single dose), can maintain intestinal barrier integrity, immune function and reduce the chances of suffering URTI or URT symptoms in athletes or those undertaking heavy training. The mechanisms are not fully understood at present but there is preliminary evidence suggesting that the effects on immune function are attributable, at least in part, to small bioactive components that survive digestion and are biologically available after consumption, but further work is required. In summary, the balance of existing evidence does support the notion that bovine colostrum is beneficial for certain groups of athletes, such as those involved in strenuous training (e.g. endurance athletes), in terms of immunity and resistance to infection.

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运动后牛初乳与免疫功能的关系。
剧烈和/或长时间的运动引起免疫功能的短暂紊乱。人们普遍认为,这是运动员,特别是耐力运动员感染(如上呼吸道感染(URTI))发生率较高的一种机制。URTI或上呼吸道(URT)症状会对训练和比赛表现产生负面影响,但运动员必须进行高强度训练才能取得成功。因此,能够合理增强免疫功能和降低尿路感染风险的干预措施可能对运动员有益。牛初乳补充作为一种可能的营养对策,在剧烈或长时间运动和高强度训练期间增强(或维持)免疫功能,并降低尿路感染风险。有令人信服的证据表明,每天补充牛初乳,持续数周(以及单次剂量后急性效应的初步证据),可以保持肠道屏障完整性,免疫功能,并减少运动员或进行高强度训练的人患上呼吸道感染或上呼吸道症状的机会。其机制目前尚不完全清楚,但有初步证据表明,对免疫功能的影响至少部分归因于消化后存活并在食用后具有生物可利用性的小生物活性成分,但需要进一步的研究。总之,现有证据的平衡确实支持这样一种观点,即牛初乳对某些运动员群体有益,例如那些参与剧烈训练的运动员(如耐力运动员),在免疫力和抗感染方面。
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