Phylogenetic analysis of hepatitis e virus in northwest India.

Hepatitis research and treatment Pub Date : 2012-01-01 Epub Date: 2012-10-24 DOI:10.1155/2012/976434
Nidhi Subhash Chandra, Ramesh Roop Rai, Bharti Malhotra
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引用次数: 9

Abstract

Genotyping and subtyping are important to understand epidemiology of the hepatitis E virus so as to improve control measures to prevent transmission of virus in the community. Hence, the aim of the current study was to identify the prevalent HEV genotypes in Rajasthan in acute sporadic hepatitis E cases with varying degree of liver failure. We studied hepatitis E virus (HEV) isolates from hospitalized patients in Rajasthan, western India. In a total of seventeen HEV sequences, six acute viral hepatitis, seven acute liver failure, and 4 acute- on-chronic cases were analyzed. Subtypes 1a and 1c of HEV are prevalent in Northwest India.

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印度西北部戊型肝炎病毒的系统发育分析。
戊型肝炎病毒的基因分型和亚型分型对了解戊型肝炎病毒的流行病学,从而改进控制措施,防止病毒在社区传播具有重要意义。因此,本研究的目的是确定拉贾斯坦邦不同程度肝功能衰竭的急性散发性戊型肝炎病例中流行的HEV基因型。我们研究了印度西部拉贾斯坦邦住院患者的戊型肝炎病毒(HEV)分离株。在总共17个HEV序列中,分析了6例急性病毒性肝炎,7例急性肝功能衰竭和4例急性慢性合并病例。HEV亚型1a和1c在印度西北部流行。
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