[Residual effectiveness of temephos observed in a Mexican southeast city affected by dengue].

Q4 Medicine Revista Cubana de Medicina Tropical Pub Date : 2012-05-01
Gloria-Elsa Antonio-Arreola, Daniel Sánchez
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引用次数: 0

Abstract

Objective: To study the effect of water extraction and renewal on the residual action of temephos applied at 1ppm to cement water-storage containers at home.

Methods: The study was conducted in two stages: one, determination of the granular temephos effectiveness on wild Aedes aegypti populations in order to set the monitoring baseline; and second, the measurement of the mean rate of water extraction at home and its effect on the residual activity of temephos.

Results: The effectiveness of granular temephos was CL95 = 0.095 ppm (IC95%: 0.079-0.118). As average, it was found that 69.2% of water stored in cement containers was daily used and renewed, which means significant dilution. For the purpose of simplifying the experiments on residual activity, water was extracted and renewed at a rate of 50% every day for 2 weeks. It was found that temephos effectiveness significantly declined from day 7 on after application.

Conclusions: This rate of water extraction under study has an important effect on the residual activity of temephos. If this rate and the CL95 of granular temephos are considered in estimating the dosing, positive effects on the control of Aedes aegypti and more likely on the occurrence of resistance will be attained.

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[在受登革热影响的墨西哥东南部城市观察到双硫磷的残留效力]。
目的:研究家用水泥储水容器中双硫磷浓度为1ppm时,水提及更新对其残留作用的影响。方法:研究分两个阶段进行:一是测定颗粒双硫磷对野生埃及伊蚊种群的药效,确定监测基线;二是测定了家庭平均水萃取率及其对双硫磷残留活性的影响。结果:颗粒双硫磷的效价CL95 = 0.095 ppm (IC95%: 0.079 ~ 0.118)。平均而言,发现69.2%储存在水泥容器中的水每天被使用和更新,这意味着显著稀释。为了简化残留活性实验,每天以50%的速率提取和更新水,持续2周。结果表明,双硫磷的药效自施用后第7天起显著下降。结论:所研究的水萃取率对双硫磷残留活性有重要影响。如果在估计剂量时考虑到这一比率和颗粒双硫磷的CL95,将对控制埃及伊蚊产生积极影响,并更有可能对耐药性的产生产生影响。
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来源期刊
Revista Cubana de Medicina Tropical
Revista Cubana de Medicina Tropical Medicine-Infectious Diseases
CiteScore
0.30
自引率
0.00%
发文量
0
期刊介绍: La Revista Cubana de Medicina Tropical tiene la misión de publicar artículos científicos especializados en medicina tropical, microbiología, parasitología, epidemiología y otras especialidades afines. Se distribuye directamente por el editor a los suscriptores en formato impreso (ISSN 0375-0760). Está dirigida a profesionales y técnicos en el campo de la medicina tropical, microbiología, parasitología y epidemiología. Recibe contribuciones en idioma español, inglés y portugués sin distinción en el país de procedencia.
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