Realization of a poro-elastic ultrasound replica of pulmonary tissue.

Biomatter Pub Date : 2012-01-01 DOI:10.4161/biom.19835
Andrea Spinelli, Bruna Vinci, Annalisa Tirella, Marco Matteucci, Luna Gargani, Arti Ahluwalia, Claudio Domenici, Eugenio Picano, Piero Chiarelli
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Abstract

In this work we describe the fabrication of a biocompatible hydrophilic scaffold composed of cross-linked gelatin that mimics the porous three-dimensional structure of pulmonary tissue as well as its water content and mechanical properties. The lung replica also reproduces the characteristic sonographic signs of pulmonary interstitial syndrome, the B-lines or ultrasound lung comets.

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实现肺组织的孔弹性超声波复制品。
在这项工作中,我们描述了一种由交联明胶组成的生物相容性亲水支架的制作过程,它模仿了肺组织的多孔三维结构及其含水量和机械性能。该肺复制品还再现了肺间质综合征的特征性声学标志--B 线或超声肺彗星。
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