[Sequence of viral infection associated to pregnancy in a dengue outbreak in Santiago de Cuba in 2006].

Q4 Medicine Revista Cubana de Medicina Tropical Pub Date : 2011-05-01

Reinaldo López Barroso, Meidys María Macias Navarro, María G Guzmán Tirado, Mayling Alvarez Vera

{"title":"[Sequence of viral infection associated to pregnancy in a dengue outbreak in Santiago de Cuba in 2006].","authors":"Reinaldo López Barroso, Meidys María Macias Navarro, María G Guzmán Tirado, Mayling Alvarez Vera","doi":"","DOIUrl":null,"url":null,"abstract":"Introduction: several dengue outbreaks have taken place in Santiago de Cuba province in the last few years, in which pregnant women have been involved.Objectives: to determine the immunity and to describe the role of dengue infection and its sequence.Methods: an observational and descriptive study was conducted to characterize dengue immunity in mothers and children after 10 and 12 months of birth and to determine the influence of certain viral infection sequences in pregnant women who suffered this disease during the dengue 3 epidemics in Santiago de Cuba. To this end, serum samples from 25 females tested dengue 3-positive and from children born to them after 10 and 12 months of childbirth were studied. IgG titers and viral infection sequences were determined and analyzed according to the World Health Organization dengue classification criteria.Results: the children did not present with the antibodies and the viral infection sequences associated to mothers; in order of frequency, the same percentage was observed in DEN2/DEN3, DEN1/DEN2/DEN3 (21,74 %); but lower percentage in DEN1/DEN3 (17,39 %).Conclusions: the children did not develop humoral immunity (IgG) despite some manifestations inherent to the disease. The secondary infections prompted the most serious forms of the disease.","PeriodicalId":35915,"journal":{"name":"Revista Cubana de Medicina Tropical","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Cubana de Medicina Tropical","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Introduction: several dengue outbreaks have taken place in Santiago de Cuba province in the last few years, in which pregnant women have been involved.

Objectives: to determine the immunity and to describe the role of dengue infection and its sequence.

Methods: an observational and descriptive study was conducted to characterize dengue immunity in mothers and children after 10 and 12 months of birth and to determine the influence of certain viral infection sequences in pregnant women who suffered this disease during the dengue 3 epidemics in Santiago de Cuba. To this end, serum samples from 25 females tested dengue 3-positive and from children born to them after 10 and 12 months of childbirth were studied. IgG titers and viral infection sequences were determined and analyzed according to the World Health Organization dengue classification criteria.

Results: the children did not present with the antibodies and the viral infection sequences associated to mothers; in order of frequency, the same percentage was observed in DEN2/DEN3, DEN1/DEN2/DEN3 (21,74 %); but lower percentage in DEN1/DEN3 (17,39 %).

Conclusions: the children did not develop humoral immunity (IgG) despite some manifestations inherent to the disease. The secondary infections prompted the most serious forms of the disease.

微信好友朋友圈 QQ好友复制链接

本刊更多论文

[2006年古巴圣地亚哥登革热疫情中与妊娠相关的病毒感染序列]。

导言:在过去几年里，古巴圣地亚哥省发生了几次登革热疫情，其中包括孕妇。目的:确定免疫和描述登革热感染的作用及其序列。方法:进行了一项观察性和描述性研究，以确定出生10个月和12个月后母亲和儿童的登革热免疫特征，并确定某些病毒感染序列对古巴圣地亚哥登革热3型流行期间患有该病的孕妇的影响。为此，研究了25名经登革热3型检测呈阳性的妇女以及她们分娩后10个月和12个月所生儿童的血清样本。根据世界卫生组织登革热分类标准，检测和分析IgG滴度和病毒感染序列。结果:患儿未出现与母亲相关的抗体和病毒感染序列;按出现频率排序，DEN2/DEN3、DEN1/DEN2/DEN3所占比例相同(21.74%);但DEN1/DEN3的比例较低(17.39%)。结论:患儿虽有该病固有的一些表现，但未出现体液免疫(IgG)。继发性感染引发了最严重的疾病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Revista Cubana de Medicina Tropical Medicine-Infectious Diseases

CiteScore

0.30

自引率

0.00%

发文量

期刊介绍： La Revista Cubana de Medicina Tropical tiene la misión de publicar artículos científicos especializados en medicina tropical, microbiología, parasitología, epidemiología y otras especialidades afines. Se distribuye directamente por el editor a los suscriptores en formato impreso (ISSN 0375-0760). Está dirigida a profesionales y técnicos en el campo de la medicina tropical, microbiología, parasitología y epidemiología. Recibe contribuciones en idioma español, inglés y portugués sin distinción en el país de procedencia.