Electrosprayed nanoparticles for drug delivery and pharmaceutical applications.

Biomatter Pub Date : 2013-07-01 Epub Date: 2013-03-19 DOI:10.4161/biom.24281
Radhakrishnan Sridhar, Seeram Ramakrishna
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引用次数: 129

Abstract

Nanotechnology based Pharma has emerged significantly and has influenced the Pharma industry up to a considerable extent. Nanoparticles technology holds a good share of the nanotech Pharma and is significant in comparison with the other domains. Electrospraying technology answers the potential needs of nanoparticle production such as scalability, reproducibility, effective encapsulation etc. Many drugs have been electrosprayed with and without polymer carriers. Drug release characteristics are improved with the incorporation of biodegradable polymer carriers which sustain the release of encapsulated drug. Electrospraying is acknowledged as an important technique for the preparation of nanoparticles with respect to pharmaceutical applications. Herein we attempted to consolidate the reports pertaining to electrospraying and their corresponding therapeutic application area.

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用于药物输送和制药应用的电喷涂纳米颗粒。
基于纳米技术的制药已经显著出现,并在很大程度上影响了制药行业。纳米颗粒技术在纳米技术制药中占有很大份额,和其他领域相比具有重要意义。电喷雾技术满足了纳米颗粒生产的潜在需求,如可扩展性、再现性、有效封装等。许多药物已经在有或没有聚合物载体的情况下进行了电喷雾。通过引入可生物降解的聚合物载体来改善药物释放特性,所述聚合物载体维持包封药物的释放。电喷雾被认为是制备纳米颗粒的重要技术。在此,我们试图整合与电喷雾及其相应的治疗应用领域有关的报告。
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