Genetic characterization of porcine circovirus type 2 from pigs with porcine circovirus associated diseases in Argentina.

ISRN veterinary science Pub Date : 2011-05-30 Print Date: 2011-01-01 DOI:10.5402/2011/560905
Ariel Pereda, Pablo Piñeyro, Ana Bratanich, María Alejandra Quiroga, Danilo Bucafusco, María Isabel Craig, Javier Cappuccio, Mariana Machuca, Agustina Rimondi, Marina Dibárbora, Hector Ramón Sanguinetti, Carlos Juan Perfumo
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引用次数: 11

Abstract

Porcine circovirus type 2 (PCV-2) has been associated with syndromes grouped by the term porcine circovirus associated diseases (PCVAD). The PCV-2 isolates have been grouped into two major groups or genotypes according to their nucleotide sequence of whole genomes and/or ORF-2: PCV-2b, which have, in turn, been subdivided into three clusters (1A-1C), and PCV-2a, which has been subdivided into five clusters (2A-2E). In the present study, we obtained 16 sequences of PCV-2 from different farms from 2003 to 2008, from animals with confirmatory diagnosis of PCVAD. Since results showed an identity of 99.8% among them, they were grouped within a common cluster 1A-B. This preliminary study suggests a stable circulation of PCV-2b among the Argentinean pig population.

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阿根廷猪圆环病毒相关疾病猪圆环病毒2型的遗传特征
猪圆环病毒2型(PCV-2)与按术语猪圆环病毒相关疾病(PCVAD)分组的综合征相关。根据其全基因组和/或ORF-2的核苷酸序列,PCV-2分离物被分为两大类或基因型:PCV-2b,又被细分为3个簇(1A-1C), PCV-2a,被细分为5个簇(2A-2E)。在本研究中,我们从2003年至2008年的不同猪场,从确诊为PCVAD的动物中获得了16个PCV-2序列。由于结果显示它们之间的同一性为99.8%,因此将它们归为一个共同的聚类1A-B。这一初步研究表明PCV-2b在阿根廷猪群中稳定传播。
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