Founding an adverse drug reaction (ADR) network: a method for improving doctors spontaneous ADR reporting in a general hospital.

IF 2.9 4区 医学 Journal of Clinical Pharmacology Pub Date : 2013-11-01 Epub Date: 2013-08-19 DOI:10.1002/jcph.149
Lee Hilary Goldstein, Maya Berlin, Walid Saliba, Mazen Elias, Matitiyahu Berkovitch
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引用次数: 25

Abstract

Adverse drug reactions (ADR) are underreported by doctors despite numerous efforts. We aimed to determine if establishing an "ADR reporting doctor's network" within a hospital would increase the quantity of ADRs reported by hospital doctors. One hundred hospital doctors joined the network. Email reminders were sent to network members during the 1 year study period, conveying information about ADRs reported, amusingly and pleasantly reminding them to report ADRs in minimal detail, by phone, email, text message or mail to the Clinical Pharmacology Unit, who would further complete the report. A total of 114 ADRs were reported during the study period in comparison to 48, 26, and 17 in the previous 3 years (2008, 2009, 2010, respectively). In the 3 years prior, doctors reported 41.7% of the reported ADRs whereas in the study period, doctors reported 74.3% of ADRs (P < .001), reflecting an 80% increase in doctors reports. Ninety seven percent of doctors' reports were of ADR network members. Thirty-four (34%) network members reported an ADR during the study period and 31 of the 34 reporters had never reported ADRs before becoming network members. Establishing an ADR network of doctors substantially increases ADR reporting amongst its members.

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建立药品不良反应(ADR)网络:提高综合医院医生自发上报ADR的方法。
药物不良反应(ADR)被医生低估了,尽管许多努力。我们的目的是确定在医院内建立“ADR报告医生网络”是否会增加医院医生报告的ADR数量。100名医院医生加入了这个网络。在1年的研究期间,向网络成员发送电子邮件提醒,传达所报告的不良反应信息,以有趣和愉快的方式提醒他们以最小的细节报告不良反应,通过电话、电子邮件、短信或邮件通知临床药理学组,后者将进一步完成报告。在研究期间共报告了114例不良反应,而前3年(分别为2008年、2009年和2010年)分别为48例、26例和17例。在前3年,医生报告的不良反应占报告的41.7%,而在研究期间,医生报告的不良反应占74.3% (P
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来源期刊
Journal of Clinical Pharmacology
Journal of Clinical Pharmacology PHARMACOLOGY & PHARMACY-
自引率
3.40%
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期刊介绍: The Journal of Clinical Pharmacology (JCP) is a Human Pharmacology journal designed to provide physicians, pharmacists, research scientists, regulatory scientists, drug developers and academic colleagues a forum to present research in all aspects of Clinical Pharmacology. This includes original research in pharmacokinetics, pharmacogenetics/pharmacogenomics, pharmacometrics, physiologic based pharmacokinetic modeling, drug interactions, therapeutic drug monitoring, regulatory sciences (including unique methods of data analysis), special population studies, drug development, pharmacovigilance, womens’ health, pediatric pharmacology, and pharmacodynamics. Additionally, JCP publishes review articles, commentaries and educational manuscripts. The Journal also serves as an instrument to disseminate Public Policy statements from the American College of Clinical Pharmacology.
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