Nanorod-Shaped Basic Al2O3 Catalyzed N,N-Diformylation of Bisuracil Derivatives: A Greener "NOSE" Approach.

ISRN Organic Chemistry Pub Date : 2013-06-26 eCollection Date: 2013-01-01 DOI:10.1155/2013/793159
Vijay K Das, Ashim J Thakur
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Abstract

A feasible "NOSE" (nanoparticles-catalyzed organic synthesis enhancement) protocol has been developed for N,N-diformylation of bisuracil derivatives using nano-Al2O3 rods as an efficient, inexpensive, and recyclable catalyst under solvent-free reaction condition at 40°C. The catalyst was reused up to the 4th cycle without affecting the rate and yield of the N,N-diformylation products appreciably.

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纳米棒状碱性氧化铝催化双尿嘧啶衍生物的N,N-二甲酰化:一种更环保的“鼻子”方法。
在40°C无溶剂条件下,采用纳米al2o3棒作为高效、廉价、可回收的催化剂,开发了一种可行的“NOSE”(纳米颗粒催化有机合成增强)方案,用于双脲嘧啶衍生物的N,N-二甲酰化反应。该催化剂可重复使用至第4次循环,对N,N-二甲酰化产物的速率和收率没有明显影响。
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