Insight, neurocognition, and schizophrenia: predictive value of the wisconsin card sorting test.

IF 3.6 Q1 PSYCHIATRY Schizophrenia Research and Treatment Pub Date : 2013-01-01 Epub Date: 2013-11-04 DOI:10.1155/2013/696125
John Stratton, Philip T Yanos, Paul Lysaker
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引用次数: 8

Abstract

Lack of insight in schizophrenia is a key feature of the illness and is associated with both positive and negative clinical outcomes. Previous research supports that neurocognitive dysfunction is related to lack of insight, but studies have not examined how neurocognition relates to change in insight over time. Therefore, the current study sought to understand how performance on the Wisconsin Card Sorting Test (WCST) differed between participants with varying degrees of change in insight over a 6-month period. Fifty-two patients with schizophrenia or schizoaffective disorder were administered the WCST and Positive and Negative Syndrome Scale (PANSS) at baseline, and the PANSS was again administered at a 6-month follow-up assessment. Results indicated that while neurocognition was related to insight at baseline, it was not related to subsequent change in insight. The implications of findings for conceptualization and assessment of insight are discussed.

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洞察力,神经认知和精神分裂症:威斯康星卡片分类测试的预测价值。
对精神分裂症缺乏洞察力是该疾病的一个关键特征,并与积极和消极的临床结果相关。先前的研究支持神经认知功能障碍与缺乏洞察力有关,但研究并没有研究神经认知与洞察力随时间变化的关系。因此,本研究试图了解在6个月的时间里,不同程度的洞察力变化的参与者在威斯康星卡片分类测试(WCST)上的表现是如何不同的。52例精神分裂症或分裂情感性障碍患者在基线时进行WCST和阳性和阴性综合征量表(PANSS),并在6个月的随访评估中再次进行PANSS。结果表明,虽然神经认知与基线时的洞察力有关,但与随后的洞察力变化无关。研究结果的含义概念化和评估的洞察力进行了讨论。
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来源期刊
CiteScore
4.60
自引率
0.00%
发文量
2
审稿时长
14 weeks
期刊介绍: Schizophrenia Research and Treatment is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies related to all aspects of schizophrenia.
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