Excellent ultrafiltration and clearance after more than 12 years of peritoneal dialysis: two case reports.

Barbara G Delano, Marcia Joseph, Adina Luboa, Nadage Richard, Anthony J Joseph
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Abstract

Because of a higher (but improving) incidence of technique failure, peritoneal dialysis (PD) is not thought to equal hemodialysis (HD) for long-term use. Other than death and transplantation, the reasons that patients leave PD include peritonitis, catheter problems, patient burnout, and (in long-duration patients) the development of encapsulating peritoneal sclerosis or ultrafiltration failure. Here, we report 2 patients who have been on continuous ambulatory PD continuously for more than 12 years, maintaining good ultrafiltration and clearances. In the case reports, we suggest potential reasons for the long duration of therapy in these women. We conclude that, in some patients on continuous ambulatory PD who sparingly use very hyperosmolar dextrose solutions and who are able to avoid frequent episodes of peritonitis, long-term PD is possible and may not require transition to HD.

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12年以上腹膜透析后的超滤和清除率:2例报告。
由于技术失败率较高(但有所改善),腹膜透析(PD)并不等同于长期使用血液透析(HD)。除死亡和移植外,患者离开PD的原因包括腹膜炎、导管问题、患者倦怠以及(长期患者)包膜性腹膜硬化或超滤功能衰竭的发展。在这里,我们报告了2例连续门诊PD治疗超过12年的患者,保持了良好的超滤和清除率。在病例报告中,我们提出了这些妇女长期接受治疗的潜在原因。我们的结论是,在一些持续的动态PD患者中,他们很少使用高渗葡萄糖溶液,并且能够避免频繁的腹膜炎发作,长期PD是可能的,并且可能不需要过渡到HD。
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