Clinical outcomes in elderly (more than 80 years of age) peritoneal dialysis patients: five years' experience at two centers.

Takanori Otowa, Tsutomu Sakurada, Motonori Nagasawa, Sayaka Shimizu, Takeshi Yokoyama, Nagayuki Kaneshiro, Yusuke Konno, Yugo Shibagaki, Kenjiro Kimura
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Abstract

The proportion of elderly people requiring renal replacement therapy has been increasing in Japan. Although several studies have shown the benefits of peritoneal dialysis (PD) in the elderly, few have reported on outcomes, including prognosis, in elderly PD patients, especially those more than 80 years of age. The purpose of the present study was to evaluate clinical outcomes in elderly (more than 80 years of age) PD patients. We retrospectively evaluated the medical records of elderly PD patients who commenced PD between 2007 and 2011. The frequency of perioperative complications, rate of PD-associated peritonitis, technique survival, overall survival, and utilization of nursing-care insurance systems were investigated as clinical outcomes. The 12 patients eligible for this study (7 men, 5 women; mean age: 85 +/- 3 years) had a median duration of follow-up of 1.2 years (interquartile range: 0.65-1.74 years). Perioperative complications were not observed in any of the patients. The frequency of PD-associated peritonitis was 1 episode in 56 months. During follow-up, 6 patients died, and 3 patients switched to hemodialysis because of tunnel infection or lack of family support. The overall survival rate at 12 months was 83%. Nursing-care insurance was used by 63% of patients. In elderly patients, it is important to predict the potential short-term issues at the initiation of PD to facilitate implementation of social services, such as home-visit nursing-care services, at the time of worsening general condition.

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老年(80岁以上)腹膜透析患者的临床结果:两个中心的5年经验
在日本,需要肾脏替代治疗的老年人比例一直在增加。尽管一些研究表明腹膜透析(PD)对老年人的益处,但很少有关于老年PD患者,特别是80岁以上患者的预后的报道。本研究的目的是评估老年(80岁以上)PD患者的临床结果。我们回顾性评估了2007年至2011年间开始PD治疗的老年PD患者的医疗记录。围手术期并发症的频率、pd相关性腹膜炎的发生率、技术生存率、总生存率和护理保险系统的使用率作为临床结果进行了调查。符合本研究条件的12例患者(男性7例,女性5例;平均年龄:85±3岁),中位随访时间为1.2年(四分位数范围:0.65-1.74年)。所有患者均无围手术期并发症。pd相关性腹膜炎发生率为56个月1次。随访期间,6例患者死亡,3例患者因隧道感染或缺乏家庭支持而改用血液透析。12个月的总生存率为83%。63%的患者使用了护理保险。对于老年患者,在PD开始时预测潜在的短期问题,以促进在一般情况恶化时实施社会服务,如家访护理服务,是很重要的。
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