Treatment of Systemic Juvenile Idiopathic Arthritis with Tocilizumab - the Role of Anti-Interleukin-6 Therapy After a Decade of Treatment.

Biologics in therapy Pub Date : 2012-02-01 eCollection Date: 2012-01-01 DOI:10.1007/s13554-012-0001-6
Andreas Reiff
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引用次数: 11

Abstract

With the recent approval of tocilizumab as the first biologic for the treatment of systemic juvenile idiopathic arthritis (sJIA), an important unmet medical need for this historically challenging disease has now been met. The purpose of this review article is to revisit the established therapeutic options for sJIA, to summarize the history of the clinical trials with tocilizumab, and to discuss its role in the treatment of sJIA.

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托珠单抗治疗系统性幼年特发性关节炎-经过十年治疗后抗白细胞介素-6治疗的作用
随着tocilizumab最近被批准作为治疗系统性青少年特发性关节炎(sJIA)的首个生物制剂,这一历史上具有挑战性的疾病的一个重要的未满足的医疗需求现在已经得到满足。这篇综述文章的目的是回顾sJIA的现有治疗方案,总结tocilizumab的临床试验历史,并讨论其在sJIA治疗中的作用。
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