The Effects of Antipsychotics on Prolactin Levels and Women's Menstruation.

IF 3.6 Q1 PSYCHIATRY Schizophrenia Research and Treatment Pub Date : 2013-01-01 Epub Date: 2013-12-24 DOI:10.1155/2013/502697
S I Bargiota, K S Bonotis, I E Messinis, N V Angelopoulos
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引用次数: 62

Abstract

Introduction. Typical and atypical antipsychotic agent is currently used for treatment in the majority of patients with psychotic disorders. The aim of this review is to assess antipsychotic induced hyperprolactinaemia and the following menstrual dysfunction that affects fertility, quality of life, and therapeutic compliance of women. Method. For this purpose, Medline, PsychInfo, Cochrane library, and Scopus databases were accessed, with a focus on the publication dates between 1954 and 2012. Research of references was also performed and 78 studies were retrieved and used for the needs of this review. Results. A summary of several antipsychotics as well as frequency rates and data on hyperprolactinaemia and menstrual disorders for different agent is presented. Conclusion. Diverse prevalence rates of hyperprolactinaemia and menstrual abnormalities have been found about each medication among different studies. Menstruation plays an important role for women, thus, understanding, careful assessment, and management of hyperprolactinaemia could enhance their lives, especially when dealing with women that suffer from a psychotic disorder.

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抗精神病药物对催乳素水平及女性月经的影响。
介绍。典型和非典型抗精神病药物目前用于大多数精神病患者的治疗。本综述的目的是评估抗精神病药诱导的高泌乳素血症和随后的月经功能障碍对女性生育能力、生活质量和治疗依从性的影响。方法。为此,我们访问了Medline、PsychInfo、Cochrane图书馆和Scopus数据库,重点关注了1954年至2012年之间的出版日期。还进行了参考文献研究,检索了78项研究并用于本综述的需要。结果。本文综述了几种抗精神病药物的使用情况,并介绍了不同药物对高泌乳素血症和月经紊乱的发生率和数据。结论。在不同的研究中发现每种药物的高泌乳素血症和月经异常的患病率各不相同。月经对女性起着重要的作用,因此,了解、仔细评估和管理高泌乳素血症可以改善她们的生活,特别是当她们患有精神障碍时。
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来源期刊
CiteScore
4.60
自引率
0.00%
发文量
2
审稿时长
14 weeks
期刊介绍: Schizophrenia Research and Treatment is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies related to all aspects of schizophrenia.
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