Association of body mass index with hemoglobin concentration and iron parameters in Iranian population.

ISRN Hematology Pub Date : 2014-02-10 eCollection Date: 2014-01-01 DOI:10.1155/2014/525312
Akram Ghadiri-Anari, Narjes Nazemian, Hassan-Ali Vahedian-Ardakani
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引用次数: 51

Abstract

Background. Studies have reported that obesity has an adverse effect on iron metabolism. Obesity is characterized by chronic, low-grade, systemic inflammation and anemia of chronic disease with elevated serum ferritin and decreased level of serum iron, transferrin saturation, and hemoglobin. Therefore, we examined the association of body mass index with hemoglobin concentration and iron parameters in this study. Methods. This cross-sectional study was conducted in Yazd to assess the relation of body mass index with hemoglobin and iron parameters among 406 adult patients 18-65 years old. Diabetes and conditions that could influence body iron stores were excluded. Results. There is no difference in hemoglobin concentrations, MCV, serum iron, TIBC, transferrin saturation index, and ferritin between normal weight, overweight, and obese persons. Conclusion. Nutritional status of persons and intake of high iron foods by obese persons should be considered. Also, other inflammatory markers should be evaluated in the future studies.

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伊朗人群身体质量指数与血红蛋白浓度和铁参数的关系
背景。研究表明,肥胖对铁代谢有不利影响。肥胖的特点是慢性、低度、全身性炎症和慢性疾病的贫血,伴有血清铁蛋白升高、血清铁、转铁蛋白饱和度和血红蛋白水平降低。因此,我们在本研究中检验了体重指数与血红蛋白浓度和铁参数的关系。方法。本横断面研究在亚兹德进行,评估406名18-65岁成人患者的身体质量指数与血红蛋白和铁参数的关系。糖尿病和其他可能影响人体铁储存的疾病被排除在外。结果。在正常体重、超重和肥胖者之间,血红蛋白浓度、MCV、血清铁、TIBC、转铁蛋白饱和指数和铁蛋白没有差异。结论。应考虑肥胖人群的营养状况和高铁食物的摄入量。此外,在未来的研究中还应评估其他炎症标志物。
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