[Diagnosis and therapeutic pathways in head and neck cancers].

M Dubois, S Ballivet de Régloix, M Raynal, P Lepage, M Kossowski, Y Pons
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Abstract

Background: Cancers of uppers aero-digestives tracts represent, infrequency, the 5th cancer in the French population. Most of them (about 70%) are diagnosed at an advanced stage (stage III or IV) while they are associated with a poor prognosis (only 40% five year survival). The objective of our study was to analyze the care pathway of patients with cancers of uppers aero-digestives tracts in order to target efforts to improve the survival of these patients.

Methods: It was a descriptive and retrospective study, on medical files, on the health care pathway of patients with cancers of uppers aero-digestives tracts cared in the Head and Neck surgery department of Val de Grâce in Paris and Percy in Clamart between January 2004 and December 2006. The patients were adults with squamous cell carcinoma of uppers aero-digestives tracts.

Results: One hundred thirty-eight files of patients were analyzed. Fifty-five percent of patients were diagnosed at an advanced stage. On average patients have waited two months and twenty-one days before consulting a doctor for the first time. The time interval between the specialist consultation and the start of treatment was on average 7 weeks. The overall 5-year survival rate was 61%.

Conclusion: Squamous cell carcinoma of uppers aero-digestives tracts remains serious and has a poor diagnosis, even in a population with a high social-cultural level. The long time interval before the first consultation may be reduced by improving health education among the general practitioner (primary and secondary prevention), and by establishing health care public campaigns. This would allow earlier diagnosis, more conservative therapeutic opportunities and therefore a better prognosis.

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[头颈癌的诊断和治疗途径]。
背景:上呼吸道消化道癌症是法国人群中少见的第五大癌症。他们中的大多数(约70%)被诊断为晚期(III期或IV期),而他们的预后较差(只有40%的5年生存率)。本研究的目的是分析上消化道癌症患者的护理途径,以便有针对性地提高这些患者的生存率。方法:对2004年1月至2006年12月在巴黎Val de grance医院头颈外科和克拉马尔Percy医院头颈外科治疗的上消化道肿瘤患者的保健途径进行描述性和回顾性研究。患者为成人上消化道鳞状细胞癌。结果:对138例患者进行了分析。55%的患者被诊断为晚期。平均而言,患者在第一次咨询医生之前要等待2个月零21天。专家会诊至治疗开始的时间间隔平均为7周。总体5年生存率为61%。结论:即使在社会文化水平较高的人群中,上消化道鳞状细胞癌仍然是一种严重的疾病,但诊断率较低。通过改善对全科医生的健康教育(初级和二级预防)以及开展保健公共运动,可以缩短首次就诊前的长时间间隔。这将允许早期诊断,更保守的治疗机会,因此更好的预后。
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