Laryngeal paraganglioma mimicking a laryngeal haemangioma.

L Plisson, V Patron, Azoulay B Luna, E Babin, M Hitier
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Abstract

Paraganglioma are uncommon neuroendocrine tumours arising from extra-adrenal chromaffin cells of the autonomic nervous system. In the head and neck region, these neoplasms most commonly arise from the carotid body, the vagus nerve, and the jugulotympanic area. We present the case of a 69-year-old woman who suffered from dyspnoea and dysphonia for six months. A biopsy diagnosed a laryngeal haemangioma and a resection of the tumour was performed using supraglottic pharyngolaryngectomy. Definitive histopathological examination revealed a laryngeal paraganglioma. Laryngeal paraganglioma and haemangioma must be evoked when confronted with a submucosal vascular laryngeal tumour. In such cases biopsies should be avoided. Exhaustive imaging is a key factor in the diagnosis and should include an MRI and an arteriography in order to rule out other differential diagnoses. To our knowledge this is the first case focusing on this issue.

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喉副神经节瘤与喉血管瘤相似。
副神经节瘤是一种罕见的神经内分泌肿瘤,起源于自主神经系统的肾上腺外染色质细胞。在头颈部,这些肿瘤最常见于颈动脉体、迷走神经和颈鼓膜区。我们提出的情况下,一个69岁的妇女谁遭受呼吸困难和发音困难六个月。活组织检查诊断为喉部血管瘤,并采用声门上咽切除术切除肿瘤。最终组织病理学检查显示为喉副神经节瘤。喉副神经节瘤和血管瘤必须唤起当面对粘膜下血管性喉部肿瘤。在这种情况下,应避免活检。详尽成像是诊断的关键因素,应包括MRI和动脉造影,以排除其他鉴别诊断。据我们所知,这是第一个关注这个问题的案例。
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