Predictors of mortality after acute stroke a prospective hospital based study.

Q3 Medicine Journal of Ayub Medical College, Abbottabad : JAMC Pub Date : 2011-04-01
Javed Akhter Rathore, Zulfiqar Ali Kango, Adnan Mehraj
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Abstract

Background: The stroke is third leading cause of death in world and 10% of patients with an acute ischemic stroke die within 30 days. Various clinical variables have been implicated as predictors of final outcome of acute stroke. The study was aimed to identify predictors of mortality after an acute stroke.

Material and methods: This prospective study included 149 consecutive patients of acute Hospital Muzaffarabad, Azad Kashmir. The outcome as mortality measures used were Modified Ranking Scale (mRS) and Glasgow Coma Scale (GCS). Examination included clinical, neurological evaluation, laboratory tests, and brain CT. The follow-ups at 14 days were done for all patients.

Results: Hospital mortality was 17.4% (26/149) within 14 days. Age and gender had no impact on mortality. Hypertension (p = 0.008), smoking (p = 0.056)), brain infarction (p = < 0.001), hemorrhagic stroke (p = < 0.001), diabetes (p = 0.292), atrial fibrillation (p < 0.001), high mRS (p < 0.001), low GCS score (p < 0.001), on admission were important predictors of mortality.

Conclusions: We report 17.4% mortality at 14 days. Mortality associated with acute stroke needs prevention and control of risk factors.

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急性中风后死亡率的预测因素:一项前瞻性医院研究。
背景:中风是世界上第三大死亡原因,10%的急性缺血性中风患者在30天内死亡。各种临床变量被认为是急性卒中最终结局的预测因子。该研究旨在确定急性中风后死亡率的预测因素。材料和方法:本前瞻性研究纳入了149例连续急性患者穆扎法拉巴德医院,阿扎德克什米尔。结果作为死亡率测量使用的是修改排名量表(mRS)和格拉斯哥昏迷量表(GCS)。检查包括临床、神经学评估、实验室检查和脑CT。所有患者均在第14天进行随访。结果:14天住院死亡率为17.4%(26/149)。年龄和性别对死亡率没有影响。入院时高血压(p = 0.008)、吸烟(p = 0.056)、脑梗死(p = < 0.001)、出血性卒中(p = < 0.001)、糖尿病(p = 0.292)、房颤(p < 0.001)、高mRS (p < 0.001)、低GCS评分(p < 0.001)是死亡率的重要预测因素。结论:我们报告了17.4%的14天死亡率。与急性脑卒中相关的死亡率需要预防和控制危险因素。
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