Gaps in clinical prevention and treatment for alcohol use disorders: costs, consequences, and strategies.

IF 6.8 1区 医学 Q1 SUBSTANCE ABUSE Alcohol Research : Current Reviews Pub Date : 2013-01-01
Mark L Willenbring
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Abstract

Heavy drinking causes significant morbidity, premature mortality, and other social and economic burdens on society, prompting numerous prevention and treatment efforts to avoid or ameliorate the prevalence of heavy drinking and its consequences. However, the impact on public health of current selective (i.e., clinical) prevention and treatment strategies is unclear. Screening and brief counseling for at-risk drinkers in ambulatory primary care has the strongest evidence for efficacy, and some evidence indicates this approach is cost-effective and reduces excess morbidity and dysfunction. Widespread implementation of screening and brief counseling of nondependent heavy drinkers outside of the medical context has the potential to have a large public health impact. For people with functional dependence, no appropriate treatment and prevention approaches currently exist, although such strategies might be able to prevent or reduce the morbidity and other harmful consequences associated with the condition before its eventual natural resolution. For people with alcohol use disorders, particularly severe and recurrent dependence, treatment studies have shown improvement in the short term. However, there is no compelling evidence that treatment of alcohol use disorders has resulted in reductions in overall disease burden. More research is needed on ways to address functional alcohol dependence as well as severe and recurrent alcohol dependence.

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临床预防和治疗酒精使用障碍方面的差距:成本、后果和策略。
酗酒会导致严重的发病率、过早死亡,并给社会带来其他社会和经济负担,促使大量预防和治疗努力避免或改善酗酒的流行及其后果。然而,目前选择性(即临床)预防和治疗策略对公众健康的影响尚不清楚。在门诊初级保健中对高危饮酒者进行筛查和简短咨询的有效性有最有力的证据,一些证据表明这种方法具有成本效益,并减少了过量的发病率和功能障碍。在医学范围之外,对非依赖性重度饮酒者进行筛查和简短咨询的广泛实施可能会对公共卫生产生重大影响。对于有功能依赖的人,目前还没有适当的治疗和预防方法,尽管这些策略可能能够在最终自然解决之前预防或减少与疾病相关的发病率和其他有害后果。对于有酒精使用障碍的人,特别是严重和反复依赖的人,治疗研究表明短期内会有所改善。然而,没有令人信服的证据表明酒精使用障碍的治疗导致总体疾病负担的减少。需要更多的研究来解决功能性酒精依赖以及严重和复发性酒精依赖的方法。
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期刊介绍: Alcohol Research: Current Reviews (ARCR) is an open-access, peer-reviewed journal published by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) at the National Institutes of Health. Starting from 2020, ARCR follows a continuous, rolling publication model, releasing one virtual issue per yearly volume. The journal offers free online access to its articles without subscription or pay-per-view fees. Readers can explore the content of the current volume, and past volumes are accessible in the journal's archive. ARCR's content, including previous titles, is indexed in PubMed, PsycINFO, Scopus, and Web of Science.
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