The discovery of immunoglobulin e and its role in allergy.

Chemical immunology and allergy Pub Date : 2014-01-01 Epub Date: 2014-05-22 DOI:10.1159/000358621
S G O Johansson
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引用次数: 5

Abstract

Immunoglobulin E (IgE) was discovered in 1967. Today, more than 40 years after the discovery, the normal beneficial function in the body of this enigmatic immunoglobulin still remains unclear. However, ever since the discovery new knowledge about allergic diseases and allergens, new treatments and new diagnostic tools have continued to emerge as a direct result of our ability to identify and measure IgE and IgE antibodies.

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免疫球蛋白e的发现及其在过敏中的作用。
免疫球蛋白E (IgE)于1967年被发现。在发现免疫球蛋白40多年后的今天,这种神秘的免疫球蛋白在人体中的正常有益功能仍不清楚。然而,自从发现关于过敏性疾病和过敏原的新知识以来,新的治疗方法和新的诊断工具不断出现,这是我们识别和测量IgE和IgE抗体能力的直接结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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Historical background, definitions and differential diagnosis. Immunological basis of food allergy (IgE-mediated, non-IgE-mediated, and tolerance). Food allergens: molecular and immunological aspects, allergen databases and cross-reactivity. Epidemiology: international point of view, from childhood to adults, food allergens. Food allergy in childhood (infancy to school age).
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