Traditional knowledge and formulations of medicinal plants used by the traditional medical practitioners of bangladesh to treat schizophrenia like psychosis.

IF 3.6 Q1 PSYCHIATRY Schizophrenia Research and Treatment Pub Date : 2014-01-01 Epub Date: 2014-06-30 DOI:10.1155/2014/679810
Md Nasir Ahmed, Md Nur Kabidul Azam
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Abstract

Schizophrenia is a subtle disorder of brain development and plasticity; it affects the most basic human processes of perception, emotion, and judgment. In Bangladesh the traditional medical practitioners of rural and remote areas characterized the schizophrenia as an insanity or a mental problem due to possession by ghosts or evil spirits and they have used various plant species' to treat such symptoms. The aim of the present study was to conduct an ethnomedicinal plant survey and documentation of the formulations of different plant parts used by the traditional medical practitioners of Rangamati district of Bangladesh for the treatment of schizophrenia like psychosis. It was observed that the traditional medical practitioners used a total of 15 plant species to make 14 formulations. The plants were divided into 13 families, used for treatment of schizophrenia and accompanying symptoms like hallucination, depression, oversleeping or insomnia, deterioration of personal hygiene, forgetfulness, and fear due to evil spirits like genies or ghost. A search of the relevant scientific literatures showed that a number of plants used by the medicinal practitioners have been scientifically validated in their uses and traditional medicinal knowledge has been a means towards the discovery of many modern medicines. Moreover, the antipsychotic drug reserpine, isolated from the dried root of Rauvolfia serpentina species, revolutionized the treatment of schizophrenia. So it is very much possible that formulations of the practitioner, when examined scientifically in their entireties, can form discovery of lead compounds which can be used as safe and effective antipsychotic drug to treat schizophrenia.

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孟加拉国传统医师治疗精神分裂症(如精神病)的传统知识和药用植物配方。
精神分裂症是大脑发育和可塑性的一种微妙失调;它影响人类最基本的感知、情感和判断过程。在孟加拉国,农村和偏远地区的传统行医者认为精神分裂症是一种精神错乱或因鬼魂或邪灵附体而导致的精神问题,他们使用各种植物物种来治疗此类症状。本研究的目的是对孟加拉国兰加马蒂地区的传统医师用于治疗精神分裂症(如精神病)的不同植物部分的配方进行民族药用植物调查和记录。据观察,传统医师共使用 15 种植物配制了 14 种配方。这些植物被分为 13 个科,用于治疗精神分裂症及其伴随症状,如幻觉、抑郁、过度睡眠或失眠、个人卫生恶化、健忘以及对精灵或鬼魂等邪灵的恐惧。对相关科学文献的检索表明,药师使用的许多植物的用途已得到科学验证,传统医药知识是发现许多现代药物的一种手段。此外,从 Rauvolfia serpentina 的干燥根中分离出来的抗精神病药物 reserpine 彻底改变了精神分裂症的治疗方法。因此,如果对从业人员的配方进行全面的科学研究,就很有可能发现可用作治疗精神分裂症的安全有效的抗精神病药物的先导化合物。
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来源期刊
CiteScore
4.60
自引率
0.00%
发文量
2
审稿时长
14 weeks
期刊介绍: Schizophrenia Research and Treatment is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies related to all aspects of schizophrenia.
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