Mian Li, Tian Ge Wang, Yu Xu, Jie Zhang, Bai Hui Xu, Min Xu, Yu Hong Chen, Jie Li Lu, Yu Fang Bi, Wei Qing Wang, Yan Yun Gu, Guang Ning
{"title":"Association of bisphenol a exposure with circulating sex hormone concentrations in men and postmenopausal women.","authors":"Mian Li, Tian Ge Wang, Yu Xu, Jie Zhang, Bai Hui Xu, Min Xu, Yu Hong Chen, Jie Li Lu, Yu Fang Bi, Wei Qing Wang, Yan Yun Gu, Guang Ning","doi":"10.3967/bes2014.096","DOIUrl":null,"url":null,"abstract":"<p><p>A total of 1116 middle-aged and elderly men and 1442 postmenopausal women were recruited in this study. Whether bisphenol A exposure was associated with circulating sex hormone concentrations was studied. Univariate analysis revealed that the urinary bisphenol A concentration was negatively correlated with the serum levels of luteinizing hormone (β=-0.061, P<0.0001) and follicle-stimulating hormone (β=-0.086, P<0.0001) in men, and with the serum levels of follicle-stimulating hormone (β=-0.037, P=0.018) and sex hormone-binding globulin (β=-0.043, P=0.006) in women. However, no significant association was observed between the serum levels of urinary bisphenol A and circulating sex hormone after adjustment for the potential confounders. </p>","PeriodicalId":9108,"journal":{"name":"Biomedical and environmental sciences : BES","volume":"27 8","pages":"633-6"},"PeriodicalIF":0.0000,"publicationDate":"2014-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical and environmental sciences : BES","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3967/bes2014.096","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
A total of 1116 middle-aged and elderly men and 1442 postmenopausal women were recruited in this study. Whether bisphenol A exposure was associated with circulating sex hormone concentrations was studied. Univariate analysis revealed that the urinary bisphenol A concentration was negatively correlated with the serum levels of luteinizing hormone (β=-0.061, P<0.0001) and follicle-stimulating hormone (β=-0.086, P<0.0001) in men, and with the serum levels of follicle-stimulating hormone (β=-0.037, P=0.018) and sex hormone-binding globulin (β=-0.043, P=0.006) in women. However, no significant association was observed between the serum levels of urinary bisphenol A and circulating sex hormone after adjustment for the potential confounders.
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