Impact of Asthma on the Severity of Serious Pneumococcal Disease.

Epidemiology (Sunnyvale, Calif.) Pub Date : 2011-12-25 DOI:10.4172/2161-1165.S3-001

Ravneet K Dhillon, Barbara P Yawn, Kwang Ha Yoo, Thomas G Boyce, Robert M Jacobson, Michaela E McGree, Amy L Weaver, Young J Juhn

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引用次数: 5

Abstract

We recently reported an increased risk of serious pneumococcal disease (SPD) in asthmatics. Little is known about the impact of asthma status on the severity of SPD. We compared the severity of serious pneumococcal disease (SPD) between patients with asthma and those without asthma. The study subjects were Rochester, Minnesota residents who developed SPD between 1964 and 1983. SPD and asthma status were ascertained by using explicit predetermined criteria Severity of SPD was assessed using intensive care unit (ICU) admission rate and total days of ICU stay and hospitalization associated with treatment for SPD. We found that there were no significant differences in severity outcomes between asthmatics (n=11) and non-asthmatics (n=163). Asthma status may increase the risk of SPD but not influence its severity. However, given a small sample size of our study, a larger study needs to be considered to clarify the relationship between asthma and severity of SPD.

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哮喘对严重肺炎球菌疾病严重程度的影响

我们最近报道了哮喘患者患严重肺炎球菌病(SPD)的风险增加。关于哮喘状态对SPD严重程度的影响知之甚少。我们比较了哮喘患者和非哮喘患者的严重肺炎球菌病(SPD)的严重程度。研究对象是明尼苏达州罗彻斯特市的居民，他们在1964年至1983年间患有SPD。使用明确的预定标准确定SPD和哮喘状态，使用重症监护病房(ICU)入院率、ICU总住院天数和与SPD治疗相关的住院时间来评估SPD的严重程度。我们发现哮喘患者(n=11)和非哮喘患者(n=163)在严重程度结局上没有显著差异。哮喘状态可能增加SPD的风险，但不影响其严重程度。然而，鉴于我们的研究样本量较小，需要考虑更大规模的研究来阐明哮喘与SPD严重程度之间的关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Epidemiology (Sunnyvale, Calif.)

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