Aripiprazole combined with other psychotropic drugs in pregnancy: two case reports.

Abstract

Maternal exposure to second generation antipsychotics during pregnancy has been associated with some negative effects for both mothers and infants. Aripiprazole is becoming more readily used, although data regarding its use in pregnancy are limited. Additionally there are limited data with regards to the impact of polypharmacy on pregnancy outcomes. Given the relative paucity of information related to aripiprazole use in pregnancy it is difficult to counsel women on potential risks or side effects. We present two cases that illustrate the use of aripiprazole as a part of a polypharmacy regimen in pregnancy and describe the pregnancy outcomes in an effort to help clinicians facing complex treatment decisions in pregnancy.