Synthesis Antimicrobial and Anticancer Evaluation of 1-Aryl-5-(o-methoxyphenyl)-2-S-benzyl Isothiobiurets.

International Journal of Medicinal Chemistry Pub Date : 2014-01-01 Epub Date: 2014-11-20 DOI:10.1155/2014/352626
Mohammed M Ansari, Shirish P Deshmukh, Rizwan Khan, Mohammed Musaddiq
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引用次数: 11

Abstract

A series of S-benzyl aryl thiourea were condensed with o-Methoxy phenyl isocyanate to yield respective isothiobiuret derivatives. The newly synthesized compounds were characterized by (1)H-NMR, IR, and Mass Spectral studies and tested for biological activities.

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1-芳基-5-(邻甲氧基苯基)-2- s -苄基异硫脲的合成、抗菌及抗癌评价
一系列s -苄基芳基硫脲与邻甲氧基苯基异氰酸酯缩合,得到了相应的异硫脲衍生物。新合成的化合物通过(1)H-NMR、IR和质谱进行了表征,并进行了生物活性测试。
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期刊介绍: International Journal of Medicinal Chemistry is a peer-reviewed, Open Access journal that publishes original research articles as well as review articles in all areas of chemistry associated with drug discovery, design, and synthesis. International Journal of Medicinal Chemistry is a peer-reviewed, Open Access journal that publishes original research articles as well as review articles in all areas of chemistry associated with drug discovery, design, and synthesis.
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