Ribosomopathies: mechanisms of disease.

IF 3 Q2 Medicine Clinical Medicine Insights-Blood Disorders Pub Date : 2014-08-14 eCollection Date: 2014-01-01 DOI:10.4137/CMBD.S16952
Hani Nakhoul, Jiangwei Ke, Xiang Zhou, Wenjuan Liao, Shelya X Zeng, Hua Lu
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引用次数: 75

Abstract

Ribosomopathies are diseases caused by alterations in the structure or function of ribosomal components. Progress in our understanding of the role of the ribosome in translational and transcriptional regulation has clarified the mechanisms of the ribosomopathies and the relationship between ribosomal dysfunction and other diseases, especially cancer. This review aims to discuss these topics with updated information.

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核糖体病:疾病机制。
核糖体病是由核糖体成分的结构或功能改变引起的疾病。我们对核糖体在翻译和转录调控中的作用的理解取得了进展,阐明了核糖体病变的机制以及核糖体功能障碍与其他疾病,特别是癌症之间的关系。这篇综述旨在用最新的信息来讨论这些主题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.70
自引率
0.00%
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0
审稿时长
8 weeks
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