A case of mixed adenoneuroendocrine carcinoma of the common bile duct: initially diagnosed as cholangiocarcinoma.

Korean Journal of Pathology Pub Date : 2014-12-01 Epub Date: 2014-12-31 DOI:10.4132/KoreanJPathol.2014.48.6.445
Soon Wook Lee, In Seok Lee, Yu Kyung Cho, Jae Myung Park, Sang Woo Kim, Myung-Gyu Choi, Kyu Yong Choi, Myung Ah Lee, Tae Ho Hong, Young Kyoung You, Eun-Sun Jung
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引用次数: 11

Abstract

Neuroendocrine tumors (NETs) are mostly found in the gastrointestinal tract and the pancreas. The World Health Organization (WHO) classification (2010) has been widely used to categorize NETs [1]. In the digestive system, NETs including those found within the bile ducts, are classed as NET G1 (carcinoid, mitotic count of 20 per 10 HPF and/or >20% Ki-67 index), and mixed adenoneuroendocrine carcinoma (MANEC) [1]. NETs arising from the bile duct are rare, accounting for only 1.8% of gastroenteropancreatic NETs [2]. MANECs of the common bile ducts (CBDs) are extremely rare, and only a few cases have been reported thus far [3-5]. In this study, we report a case of MANEC arising from the mid CBD.

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Korean Journal of Pathology
Korean Journal of Pathology 医学-病理学
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