The fundamentals of biotribology and its application to spine arthroplasty

Megan L. Harper MASc , Andrew Dooris PhD , Philippe E. Paré MASc
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引用次数: 23

Abstract

The biological effect of wear of articulating surfaces is a continued concern with large joint replacements and, likewise, of interest for total disc replacements. There are a number of important biotribological testing parameters that can greatly affect the outcome of a wear study in addition to the implant design and material selection. The current ASTM and ISO wear testing standards/guides for spine arthroplasty leave many choices as testing parameters. These factors include but are not limited to the sequence of kinematics and load, phasing, type of lubricant, and specimen preparation (sterilization and artificial aging). The spinal community should critically assess wear studies and be cognizant of the influence of the selected parameters on the test results.

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生物摩擦学的基本原理及其在脊柱关节置换术中的应用
关节面磨损的生物学效应在大关节置换术中一直受到关注,同样,对全椎间盘置换术也很感兴趣。除了植入物的设计和材料的选择外,还有许多重要的生物摩擦学测试参数可以极大地影响磨损研究的结果。目前的ASTM和ISO脊柱关节置换术磨损测试标准/指南留下了许多选择作为测试参数。这些因素包括但不限于运动学和载荷顺序、相位、润滑剂类型和试样制备(灭菌和人工老化)。脊柱界应该严格评估磨损研究,并认识到所选参数对测试结果的影响。
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