[Comparative efficacy of original oil escazole and nemozole suspensions in albino mice with experimental trichinosis in the muscle phase of invasion].

F P Kovalenko, I V Kukhaleva, Iu A Legon'kov
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Abstract

The efficacy of original oil escazole and nemozole suspensions in albino mice in the muscle phase of T. spiralis invasion, which was detected by lifetime diagnosis of experimental trichinosis 6 days after initiation of treatment in a daily dose of 0.3 g/kg, was 100%. Under equal experimental conditions, the oil nemozole suspension showed high toxicity and caused death in 50% of the treated animals.

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[原油艾斯卡唑与奈莫唑混悬液对实验性旋毛虫病侵袭期白化小鼠的疗效比较]。
初始剂量0.3 g/kg的原始油艾斯卡唑和奈莫唑混悬液,在实验旋毛虫病开始治疗后6天通过终生诊断检测,对螺旋体侵袭肌期白化小鼠的疗效为100%。在相同的实验条件下,油尼莫唑悬浮液显示出高毒性,50%的处理动物死亡。
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