Quality of life-in patients with differentiated thyroid cancer at the general endocrinology clinics of the University Hospital of Puerto Rico.

Mónica A Vega-Vázquez, Loida Gonzalez-Rodriguez, Eduardo J Santiago-Rodríguez, Anette Garcés-Domínguez, Lee-Ming Shum, Maribel Tírado-Gómez, Margarita Ramírez-Vick
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Abstract

Unlabelled: Differentiated thyroid cancer (DTC) can compromise the quality of life of patients. Our purpose is to investigate if the quality of life, in a cohort of patients in Puerto Rico, is affected by the diagnosis and/or treatment modalities received for DTC.

Methods: This is a cross-sectional study of 75 subjects with DTC. A Spanish version of the University of Washington Quality of Life Questionnaire was used, including multiple aspects of physical and social functioning. Descriptive and bivariate analysis between domain scores and variables of interest were performed.

Results: 82.7% of the patients reported that their health was the same or better than it was before treatment. The mean composite score obtained was 82.3, reflecting an overall little effect on quality of life. Patients diagnosed with DTC at an age of > or =45 years reported a significantly better score on the pain domain when compared with those diagnosed earlier (p < 0.05). Patient who received >150 mCi of radioiodine had a tendency towards a worse score on the same domain (p = 0.05).

Conclusions: Our cohort reported an overall minimal effect on the quality of life of patients with DTC. Future treatment strategies should include periodic quality of life evaluations, in order to tailor therapy in this growing population.

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波多黎各大学医院普通内分泌科门诊分化型甲状腺癌患者的生活质量
未标记:分化型甲状腺癌(DTC)可危及患者的生活质量。我们的目的是调查波多黎各一组患者的生活质量是否受到DTC的诊断和/或治疗方式的影响。方法:对75例DTC患者进行横断面研究。使用了华盛顿大学生活质量调查问卷的西班牙语版本,包括身体和社会功能的多个方面。在领域分数和感兴趣的变量之间进行描述性和双变量分析。结果:82.7%的患者报告其健康状况与治疗前相同或更好。获得的平均综合得分为82.3,反映了对生活质量的总体影响很小。诊断为DTC的患者在>或=45岁时报告的疼痛域评分明显优于早期诊断的患者(p < 0.05)。放射性碘剂量大于150mci的患者在同一域评分有较差的趋势(p = 0.05)。结论:我们的队列报告了对DTC患者生活质量的总体最小影响。未来的治疗策略应包括定期的生活质量评估,以便为这一不断增长的人群量身定制治疗方案。
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