Image features of retinal astrocytic hamartoma in a patient with tuberous sclerosis complex.

眼科学报 Pub Date : 2014-12-01

Peng Zhang, Dongjie Sun, Jinting Zhu, Juan Li, Yusheng Wang

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Abstract

Purpose: To describe the image features of retinal astrocytic hamartoma in a 35-year-old male patient with tuberous sclerosis complex (TSC).

Methods: Fundus photography, fundus autofluorescence (FAF), fundus fluorescein angiography (FFA), and spectral domain optical coherence tomography (SD-OCT) were performed for this retinal astrocytic hamartoma.

Results: Fundus photography showed that the retinal astrocytic hamartoma presented as a well-circumscribed, mulberry-like lesion consisting of glistening yellowish spherules of calcification. FAF demonstrated dense hyper-autofluorescence spots corresponding to retinal astrocytic hamartoma. FFA revealed leakage from dilated retinal capillaries over the hamartoma. SD-OCT indicated moth-eaten optically empty spaces and hyperreflective dots within the lesion. The lesion surface was fluctuate.

Conclusion: FAF is a useful imaging modality for obtaining greater contrast between a retinal astrocytic hamartoma and the surrounding retina due to hyper-autofluorescence of calcification in the lesion. FFA is beneficial for monitoring the abnormal blood vessels in these lesions. SD-OCT is capable of visualization the structural details, such as the uneven surface and inner hyperreflective dots.

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结节性硬化症患者视网膜星形细胞错构瘤的影像特征。

目的:描述35岁男性结节性硬化症(TSC)患者视网膜星形细胞错构瘤的影像特征。方法:眼底摄影、眼底自体荧光(FAF)、眼底荧光素血管造影(FFA)、光谱域光学相干断层扫描(SD-OCT)检查该视网膜星形细胞错构瘤。结果:眼底摄影显示视网膜星形细胞错构瘤表现为边界清晰的桑葚样病变，由闪烁的淡黄色钙化球体组成。FAF显示密集的超自身荧光斑点，对应于视网膜星形细胞错构瘤。FFA显示错构瘤上方扩张的视网膜毛细血管渗漏。SD-OCT显示病变内虫蛀的光学空洞和高反射点。病变表面呈上下波动。结论:FAF是一种有用的成像方式，可以在视网膜星形细胞错构瘤和周围视网膜之间获得更大的对比，因为病变处的钙化高度自身荧光。FFA有利于监测病变血管的异常情况。SD-OCT能够可视化结构细节，如不均匀的表面和内部的高反射点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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