Food allergy in adolescence and adulthood.

Chemical immunology and allergy Pub Date : 2015-01-01 Epub Date: 2015-05-21 DOI:10.1159/000371669
Barbara K Ballmer-Weber
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引用次数: 15

Abstract

In young children, food allergy is usually acquired via the gastrointestinal tract and directed toward egg and milk. Adolescent and adult patients, however, mainly acquire food allergy via primary sensitization to inhalant allergens on the basis of cross-reactivity between proteins in inhalant sources and in food. This type of food allergy is frequently mediated by sensitization to broadly represented allergens, or so-called panallergens. Food allergic reactions in adult patients - similar to those in children - range in severity from very mild and local symptoms, as in contact urticaria of the oral mucosa, to systemic symptoms involving distal organs, to a fatal outcome. Plant foods, such as fruits, nuts, and vegetables, are the most prevalent allergenic foods in this age group.

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青少年和成年期的食物过敏。
在幼儿中,食物过敏通常是通过胃肠道获得的,直接针对鸡蛋和牛奶。然而,青少年和成人患者主要是通过吸入过敏原的初始致敏而获得食物过敏,这是基于吸入源和食物中的蛋白质之间的交叉反应。这种类型的食物过敏通常是由对广泛代表的过敏原或所谓的泛过敏原的致敏介导的。成人患者的食物过敏反应与儿童相似,其严重程度从非常轻微的局部症状(如口腔粘膜接触性荨麻疹)到涉及远端器官的全身性症状,再到致命的结果。植物性食物,如水果、坚果和蔬菜,是这个年龄段最常见的致敏食物。
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Historical background, definitions and differential diagnosis. Immunological basis of food allergy (IgE-mediated, non-IgE-mediated, and tolerance). Food allergens: molecular and immunological aspects, allergen databases and cross-reactivity. Epidemiology: international point of view, from childhood to adults, food allergens. Food allergy in childhood (infancy to school age).
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