Coronary levels of angiotensin-II and endothelin-I in diabetic patients with and without coronary artery disease.

Pablo I Altieri, José M Marcial, Héctor L Banchs, Nelson Escobales, María Crespo, Wilma González
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Abstract

Two groups of patients were studied to find out the levels of angiotensin-II and endothelin-I in the coronary and peripheral circulation. Group A consisted of eight patients with diabetes mellitus type 2 and coronary artery disease; and Group B with diabetes mellitus without coronary artery disease. Significant differences were found between Group A and B in the levels of both peptides peripherally and intracoronary. This shows the importance of these peptides in the origin of coronary artery disease and progression of the disease in diabetics with coronary artery disease.

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伴有和不伴有冠状动脉疾病的糖尿病患者的冠状动脉血管紧张素- ii和内皮素- i水平
研究两组患者冠状动脉和外周循环血管紧张素- ii和内皮素- i的水平。A组8例2型糖尿病合并冠心病患者;B组合并糖尿病,无冠状动脉病变。A组和B组在冠状动脉周围和冠状动脉内肽水平上均有显著差异。这显示了这些肽在冠状动脉疾病的起源和糖尿病冠状动脉疾病的进展中的重要性。
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