Samuel D Vasikaran, Sa Paul Chubb, Peter R Ebeling, Nicole Jenkins, Graham Rd Jones, Mark A Kotowicz, Howard A Morris, Hans-Gerhard Schneider, Markus J Seibel, Greg Ward
{"title":"Harmonised Australian Reference Intervals for Serum PINP and CTX in Adults.","authors":"Samuel D Vasikaran, Sa Paul Chubb, Peter R Ebeling, Nicole Jenkins, Graham Rd Jones, Mark A Kotowicz, Howard A Morris, Hans-Gerhard Schneider, Markus J Seibel, Greg Ward","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Bone turnover markers (BTMs) are classified as either formation or resorption markers. Their concentrations in blood or urine of adults are considered to reflect the rate of bone remodelling and may be of use in the management of patients with bone disease. Major inter-method differences exist for BTMs, and harmonisation of methods is currently being pursued at an international level. Based on published data, this article describes age- and sex-specific Australian consensus reference intervals for adults for serum procollagen type I amino-terminal propeptide (s-PINP) and serum β-isomerised carboxy-terminal cross-linking telopeptide of type I collagen (s-CTX). </p>","PeriodicalId":34924,"journal":{"name":"Clinical Biochemist Reviews","volume":"35 4","pages":"237-42"},"PeriodicalIF":0.0000,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310062/pdf/cbr-35-237.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Biochemist Reviews","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Biochemistry, Genetics and Molecular Biology","Score":null,"Total":0}
引用次数: 0
Abstract
Bone turnover markers (BTMs) are classified as either formation or resorption markers. Their concentrations in blood or urine of adults are considered to reflect the rate of bone remodelling and may be of use in the management of patients with bone disease. Major inter-method differences exist for BTMs, and harmonisation of methods is currently being pursued at an international level. Based on published data, this article describes age- and sex-specific Australian consensus reference intervals for adults for serum procollagen type I amino-terminal propeptide (s-PINP) and serum β-isomerised carboxy-terminal cross-linking telopeptide of type I collagen (s-CTX).
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