[BCL1 POLYMORPHISM OF GLUCOCORTICOID RECEPTOR GENE AND RESPIRATORY DISEASES].

Likars'ka sprava Pub Date : 2015-01-01
L N Prystupa, V Yu Garbuzova, V V Kmyta
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Abstract

The article analyses the results of investigating the connection between BCL1-polymorphism of glucocorticoid receptor gene and respiratory diseases. Its role in increasing sensitivity to glucocorticoids is proved here. The authors investigated the association of Bcl1 polymorphism with predisposition to bronchial asthma, chronic obstructive pulmonary disease, with the nicotine addiction degree and with progressing disorders of pulmonary function in cystic fibrosis.

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[糖皮质激素受体基因bcl1多态性与呼吸系统疾病]。
本文对糖皮质激素受体基因bcl1多态性与呼吸系统疾病关系的研究结果进行了分析。它在增加对糖皮质激素的敏感性方面的作用在这里得到了证明。作者研究了Bcl1多态性与支气管哮喘、慢性阻塞性肺疾病易感性、尼古丁成瘾程度以及囊性纤维化患者肺功能进行性障碍的关系。
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