Microsurgical arterial anastomosis in young and adult rats: an evolutive and comparative study.

IF 1.1 4区 医学 Q3 SURGERY Acta cirurgica brasileira Pub Date : 2022-09-05 eCollection Date: 2022-01-01 DOI:10.1590/acb370604
Maria Mercês Santos, Ana Cristina Aoun Tannuri, Adriana Vasconcelos Lacerda, Josiane de Oliveira Gonçalves, Luiz Roberto Schlaich Ricardi, Uenis Tannuri
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Abstract

Purpose: To evaluate the caliber of an arterial micro-anastomosis in the young growing animal using a continuous suture technique. Additionally, late morphological changes and blood flows distal to the anastomosis were evaluated.

Methods: Seventy-four Wistar rats were submitted to laparotomy to access the aorta for blood flow measurement. The aorta was sectioned using microsurgery technique and an end-to-end anastomosis with continuous suture. After a period of six months to one year, the anastomosis was checked.

Results: Regarding the size of the aortas, comparing the pre- and postoperative values, there was an increase of 13.33% in adult animals and 25% in young animals, without any difference in the blood flows.

Conclusions: The arteries of young rats show signs of growth at the site of the anastomosis performed with continuous suture.

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幼鼠和成年大鼠动脉吻合的显微外科手术:进化和比较研究。
目的:评价连续缝合技术在幼龄动物动脉微吻合术中的应用价值。此外,后期形态学变化和血流远端吻合器进行了评估。方法:74只Wistar大鼠开腹进入主动脉进行血流量测量。采用显微外科技术切开主动脉,连续缝合端到端吻合。术后6个月至1年复查吻合情况。结果:主动脉大小与术前、术后比较,成体大鼠增大13.33%,幼体大鼠增大25%,血流量无差异。结论:连续缝合后,幼龄大鼠吻合部位动脉有生长迹象。
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60
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3-8 weeks
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