The Association Between Hematologic Indices with TIMI Flow in STEMI Patients who Undergo Primary Percutaneous Coronary Intervention.

Q2 Medicine Cardiovascular and Hematological Disorders - Drug Targets Pub Date : 2022-01-01 DOI:10.2174/1871529X22666220913122046

Saeed Alipour Parsa, Saeed Nourian, Morteza Safi, Mohammad Hasan Namazi, Habib Saadat, Hossein Vakili, Vahid Eslami, Ayoub Salehi, Farshid Heidarpour Kiaee, Nasim Sohrabifar, Isa Khaheshi

{"title":"The Association Between Hematologic Indices with TIMI Flow in STEMI Patients who Undergo Primary Percutaneous Coronary Intervention.","authors":"Saeed Alipour Parsa, Saeed Nourian, Morteza Safi, Mohammad Hasan Namazi, Habib Saadat, Hossein Vakili, Vahid Eslami, Ayoub Salehi, Farshid Heidarpour Kiaee, Nasim Sohrabifar, Isa Khaheshi","doi":"10.2174/1871529X22666220913122046","DOIUrl":null,"url":null,"abstract":"Background: The Primary Percutaneous Coronary Intervention (PPCI) is the preferred therapeutic strategy for patients who experienced ST-Elevation Myocardial Infarction (STEMI).Objective: We aimed to evaluate the association of hematological indices, including hemoglobin level, platelets, White Blood Cells (WBCs) count, and MPV before PPCI with the TIMI grade flow after PPCI.Methods: STEMI patients who experienced PPCI were included in the present retrospective crosssectional study. Then participants were divided into three groups based on their post-procedural TIMI flow grades. Demographic data and hematologic indices of patients before PPCI were collected and their association with the TIMI grade flow after PPCI was evaluated. To compare the quantitative and qualitative variables, chi-square and t-tests were performed, respectively.Results: We found that elevated levels of hemoglobin and decreased levels of MPV had a significant association with an advanced grade of TIMI flow. Interestingly, in the normal range, there was a significant association between higher platelet count and TIMI-flow grade 1. Besides, TIMI flow grades 2 and 3 had a significant association with low and moderate platelets count, respectively.Conclusion: In conclusion, evaluating MPV, platelets, and hemoglobin levels before PPCI as easy and accessible parameters may be able to identify high-risk STEMI patients undergoing PPCI.","PeriodicalId":9543,"journal":{"name":"Cardiovascular and Hematological Disorders - Drug Targets","volume":" ","pages":"162-167"},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cardiovascular and Hematological Disorders - Drug Targets","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1871529X22666220913122046","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Background: The Primary Percutaneous Coronary Intervention (PPCI) is the preferred therapeutic strategy for patients who experienced ST-Elevation Myocardial Infarction (STEMI).

Objective: We aimed to evaluate the association of hematological indices, including hemoglobin level, platelets, White Blood Cells (WBCs) count, and MPV before PPCI with the TIMI grade flow after PPCI.

Methods: STEMI patients who experienced PPCI were included in the present retrospective crosssectional study. Then participants were divided into three groups based on their post-procedural TIMI flow grades. Demographic data and hematologic indices of patients before PPCI were collected and their association with the TIMI grade flow after PPCI was evaluated. To compare the quantitative and qualitative variables, chi-square and t-tests were performed, respectively.

Results: We found that elevated levels of hemoglobin and decreased levels of MPV had a significant association with an advanced grade of TIMI flow. Interestingly, in the normal range, there was a significant association between higher platelet count and TIMI-flow grade 1. Besides, TIMI flow grades 2 and 3 had a significant association with low and moderate platelets count, respectively.

Conclusion: In conclusion, evaluating MPV, platelets, and hemoglobin levels before PPCI as easy and accessible parameters may be able to identify high-risk STEMI patients undergoing PPCI.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

接受经皮冠状动脉介入治疗的 STEMI 患者血液指标与 TIMI 流量之间的关系

背景：初级经皮冠状动脉介入治疗（PPCI）是 STEMI 患者的首选治疗策略：原发性经皮冠状动脉介入治疗（PPCI）是ST段抬高型心肌梗死（STEMI）患者的首选治疗策略：我们旨在评估血液学指标（包括 PPCI 前的血红蛋白水平、血小板、白细胞（WBC）计数和 MPV）与 PPCI 后 TIMI 分级血流的关系：本回顾性横断面研究纳入了接受过 PPCI 的 STEMI 患者。然后根据患者术后的 TIMI 血流分级将其分为三组。研究人员收集了 PPCI 术前患者的人口统计学数据和血液学指标，并评估了它们与 PPCI 术后 TIMI 血流分级的关系。为了比较定量和定性变量，分别进行了卡方检验和 t 检验：结果：我们发现，血红蛋白水平升高和 MPV 水平降低与 TIMI 血流分级高级有显著关联。有趣的是，在正常范围内，较高的血小板计数与 TIMI 血流 1 级有显著关联。此外，TIMI 血流分级 2 级和 3 级分别与低血小板计数和中血小板计数显著相关：总之，在进行 PPCI 之前评估 MPV、血小板和血红蛋白水平是一项简便易行的参数，可用于识别接受 PPCI 的高危 STEMI 患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Cardiovascular and Hematological Disorders - Drug Targets Medicine-Cardiology and Cardiovascular Medicine

CiteScore

1.90

自引率

0.00%

发文量

期刊介绍： Cardiovascular & Hematological Disorders - Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in cardiovascular and hematological disorders e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in cardiovascular and hematological disorders. As the discovery, identification, characterization and validation of novel human drug targets for cardiovascular and hematological drug discovery continues to grow.