Role of Molecular Targeted Therapeutic Drugs in Treatment of Oral Squamous Cell Carcinoma: Development and Current Strategies-A Review Article.

IF 1.2 Q4 GENETICS & HEREDITY Global Medical Genetics Pub Date : 2022-09-19 eCollection Date: 2022-09-01 DOI:10.1055/s-0042-1756663

Himanshu Singh, Vedant Patel

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Abstract

Because of active advancement in the field of biomedicine, people have in-depth knowledge of biological nature of malignant tumors and are able to recognized the overexpression of different molecules such as vascular endothelial growth factor receptor, cyclin-dependent kinase, and programmed cell death receptor. Presently, various targeted therapeutic drugs are used in different clinical trials in those patients suffering from oral squamous cell carcinoma. In this review, we converse about the various targeted therapeutic drugs and their advancement in the treatment of oral squamous cell carcinoma. This review scrutinizes the existing documentation in the literature related to the targeted therapies for oral squamous cell carcinoma. English language articles were searched in various databases such as PubMed, Scopus, Science Direct, and Google Scholar. The keywords used for searching are "oral squamous cell carcinoma," "targeted therapy," and "therapeutic drugs."

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分子靶向治疗药物在口腔鳞状细胞癌治疗中的作用:进展及当前策略综述。

由于生物医学领域的积极进展，人们对恶性肿瘤的生物学性质有了深入的认识，能够识别血管内皮生长因子受体、细胞周期蛋白依赖性激酶、程序性细胞死亡受体等不同分子的过表达。目前，各种靶向治疗药物用于口腔鳞状细胞癌患者的不同临床试验。本文就口腔鳞状细胞癌的靶向治疗药物及其研究进展作一综述。本文回顾了口腔鳞状细胞癌靶向治疗的相关文献。在PubMed、Scopus、Science Direct和Google Scholar等不同的数据库中搜索英语文章。搜索的关键词是“口腔鳞状细胞癌”、“靶向治疗”和“治疗药物”。

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来源期刊

Global Medical Genetics GENETICS & HEREDITY-

自引率

11.80%

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审稿时长

14 weeks