Efficacy of conservative approaches on pain relief in patients with temporomandibular joint disorders: a systematic review with network meta-analysis.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2025-03-01 Epub Date: 2022-09-23 DOI:10.1080/08869634.2022.2126079

Martina Ferrillo, Ludovica Nucci, Amerigo Giudice, Dario Calafiore, Nicola Marotta, Giuseppe Minervini, Fabrizia d'Apuzzo, Antonio Ammendolia, Letizia Perillo, Alessandro de Sire

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引用次数: 0

Abstract

Objective: The aim of this systematic review with meta-analysis was to evaluate the efficacy of conservative interventions in pain relief in patients with intracapsular temporomandibular disorders (TMD).

Methods: PubMed, Scopus, and Web of Science were systematically searched until January 1^st, 2022 to identify randomized controlled trials (RCTs) presenting patients with diagnosis of intracapsular TMD according to the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD), conservative approaches as interventions, and pain intensity as outcome.

Results: Out of 3372 papers, 13 RCTs were included, with 844 study participants. Most of them (n = 7) investigated the efficacy of splint appliance. Meta-analysis revealed that rehabilitative interventions had a significant overall effect size of 0.75 [0.17, 1.34], reporting splint appliance and laser therapy as significantly effective treatments.

Conclusion: Findings of this systematic review with network meta-analysis suggested that conservative approaches might be effective in pain relief of intracapsular TMD patients.

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保守疗法对缓解颞下颌关节紊乱症患者疼痛的疗效：系统综述与网络荟萃分析。

目的本系统综述和荟萃分析旨在评估保守干预对缓解囊内性颞下颌关节紊乱症（TMD）患者疼痛的疗效：方法：对截至2022年1月1日的PubMed、Scopus和Web of Science进行了系统检索，以确定根据颞下颌关节紊乱诊断标准（DC/TMD）诊断为囊内TMD、以保守方法为干预措施、以疼痛强度为结果的随机对照试验（RCT）：在3372篇论文中，共纳入了13项RCT研究，共有844名参与者。其中大部分（7 篇）研究了夹板矫治器的疗效。Meta 分析显示，康复干预的总体效应大小为 0.75 [0.17, 1.34]，夹板矫形器和激光疗法的疗效显著：本系统综述和网络荟萃分析的结果表明，保守疗法对缓解囊内 TMD 患者的疼痛可能有效。

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来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464

期刊介绍： ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.