Mirror neurons and empathy-related regions in psychopathy: Systematic review, meta-analysis, and a working model.

IF 1.7 4区医学 Q4 NEUROSCIENCES Social Neuroscience Pub Date : 2022-10-01 Epub Date: 2022-10-04 DOI:10.1080/17470919.2022.2128868

Julio C Penagos-Corzo, Michelle Cosio van-Hasselt, Daniela Escobar, Rubén A Vázquez-Roque, Gonzalo Flores

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引用次数: 3

Abstract

Mirror neurons have been associated with empathy. People with psychopathic traits present low levels of empathy. To analyze this, a systematic review of fMRI studies of people with psychopathic traits during an emotional facial expression processing task was performed. The regions of interest were structures associated with the mirror neuron system: ventromedial prefrontal cortex (vmPFC), inferior parietal lobe (IPL), inferior frontal gyrus and superior temporal sulcus. The analysis was also extended to structures related to affective empathy (insula, amygdala and anterior cingulate cortex) and to two more emotional processing areas (orbitofrontal cortex and fusiform gyrus). Hypoactivation was more frequently observed in regions of the mirror neuron system from people with high psychopathic traits, as well as in the emotional processing structures, and those associated with affective empathy, except for the insula, where it presented higher activity. Differences were observed for all types of emotions. The results suggest that the mirror neuron system is altered in psychopathy and their relationship with affective empathy deficits is discussed.

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精神病中的镜像神经元和共情相关区域:系统回顾、meta分析和工作模型。

镜像神经元与同理心有关。具有精神病态特征的人表现出低水平的同理心。为了分析这一点，系统地回顾了在情绪化面部表情处理任务中具有精神病态特征的人的功能磁共振成像研究。感兴趣的区域是与镜像神经元系统相关的结构:腹内侧前额叶皮层(vmPFC)、下顶叶(IPL)、额下回和颞上沟。该分析还扩展到与情感共情相关的结构(脑岛、杏仁核和前扣带皮层)以及另外两个情感处理区域(眶额皮质和梭状回)。在具有高精神病态特征的人的镜像神经元系统区域，以及情绪处理结构和与情感同理心相关的区域，除了表现出较高活动的脑岛之外，更经常观察到失活。在所有类型的情绪中都观察到差异。结果表明，镜像神经元系统在精神病患者中发生了改变，并讨论了其与情感共情缺陷的关系。

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来源期刊

Social Neuroscience 医学-神经科学

CiteScore

3.40

自引率

5.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Social Neuroscience features original empirical Research Papers as well as targeted Reviews, Commentaries and Fast Track Brief Reports that examine how the brain mediates social behavior, social cognition, social interactions and relationships, group social dynamics, and related topics that deal with social/interpersonal psychology and neurobiology. Multi-paper symposia and special topic issues are organized and presented regularly as well. The goal of Social Neuroscience is to provide a place to publish empirical articles that intend to further our understanding of the neural mechanisms contributing to the development and maintenance of social behaviors, or to understanding how these mechanisms are disrupted in clinical disorders.