IPT coverage and determinants of care coverage in Tanzania.

IF 1.3 Q4 RESPIRATORY SYSTEM Public Health Action Pub Date : 2022-09-21 DOI:10.5588/pha.22.0018

H Manisha, W Amani, A Garrib, M Senkoro, S Mfinanga

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引用次数: 1

Abstract

Background: TB is a major cause of mortality worldwide, with the highest risk in people living with HIV/AIDS (PLWHA). Isoniazid preventive therapy (IPT), in combination with antiretroviral therapy (ART), reduces the overall incidence and mortality from TB by up to 90% among PLWHA. Tanzania has limited published data on IPT coverage among PLWHA.

Objective: To investigate coverage and determinants of IPT among PLWHA receiving care in selected care and treatment clinics in Dar es Salaam, Tanzania.

Methods: An analytical cross-sectional design to study 31,480 HIV-positive adults. Proportions and comparisons were obtained using χ² tests, while determinants for IPT were assessed using adjusted multivariable analysis.

Results: The IPT coverage among eligible PLWHA was generally low (28.9%), with increased coverage over time. The determinants for IPT coverage included age >36 years, having WHO Clinical Stages 1 and 2 compared to 3 and 4, and having normal weight, or being overweight and obesity compared to underweight.

Conclusion: IPT coverage in Dar es Salaam is very low; individuals with minor HIV disease severity were more likely to initiate IPT. This shows a possible gap in the prescribing practices among healthcare providers. More efforts to ensure IPT coverage implementation in Dar es Salaam are required.

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坦桑尼亚IPT覆盖率和保健覆盖率的决定因素。

背景:结核病是世界范围内死亡的主要原因之一，艾滋病毒/艾滋病(PLWHA)感染者的风险最高。异烟肼预防治疗与抗逆转录病毒治疗相结合，可将艾滋病感染者结核病的总发病率和死亡率降低高达90%。坦桑尼亚公布的关于艾滋病病毒携带者间IPT覆盖率的数据有限。目的:调查在坦桑尼亚达累斯萨拉姆选定的护理和治疗诊所接受治疗的PLWHA患者中IPT的覆盖率和决定因素。方法:采用横断面分析设计对31480名hiv阳性成人进行研究。采用χ2检验获得比例和比较，采用调整后的多变量分析评估IPT的决定因素。结果:在符合条件的艾滋病感染者中，IPT覆盖率普遍较低(28.9%)，随着时间的推移覆盖率有所提高。IPT覆盖率的决定因素包括年龄>36岁，与3期和4期相比具有世卫组织临床1期和2期，体重正常，或与体重不足相比超重和肥胖。结论:达累斯萨拉姆IPT覆盖率很低;HIV疾病严重程度较轻的个体更有可能开始IPT。这表明在医疗保健提供者之间的处方做法可能存在差距。需要作出更多努力，确保在达累斯萨拉姆实施IPT。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Public Health Action RESPIRATORY SYSTEM-

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期刊介绍： Launched on 1 May 2011, Public Health Action (PHA) is an official publication of the International Union Against Tuberculosis and Lung Disease (The Union). It is an open access, online journal available world-wide to physicians, health workers, researchers, professors, students and decision-makers, including public health centres, medical, university and pharmaceutical libraries, hospitals, clinics, foundations and institutions. PHA is a peer-reviewed scholarly journal that actively encourages, communicates and reports new knowledge, dialogue and controversy in health systems and services for people in vulnerable and resource-limited communities — all topics that reflect the mission of The Union, Health solutions for the poor.