Tingting Ji, Xiaodan Li, Yanzhen Li, Xuexi Zhang, Qiaoyin Liu, Jie Zhang, Nian Sun, Zhiyong Liu, Yuwei Liu, Shengcai Wang, Xin Ni
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引用次数: 0
Abstract
Ewing-like sarcomas (ELS) are round cell mesenchymal neoplasms that are highly aggressive to bone and/or soft tissue. However, they rarely occur in the nose, with no reported such cases in the medical literature to date. Here, we reported the case of a two-year-old Chinese boy who presented with a mass in the left nasal cavity. Surprisingly, the final histopathological diagnosis of the nasal mass was determined to be a subtype of ELS, BCOR-rearranged sarcoma. Therefore, we retrospectively analyzed the clinical data of this case and reviewed the relevant literature on ELS and BCOR-rearranged sarcoma. The purpose of this article is to provide new insights into the clinical characteristics of children with BCOR-rearranged Ewing-like sarcoma and to improve the understanding of this disease.
尤文样肉瘤（ELS）是一种圆形细胞间充质肿瘤，对骨骼和/或软组织具有高度侵袭性。然而，它们很少发生在鼻部，迄今为止医学文献中还没有此类病例的报道。在此，我们报告了一例两岁中国男孩的病例，他因左鼻腔肿块而就诊。令人惊讶的是，鼻腔肿块的最终组织病理学诊断被确定为 ELS 的一种亚型，即 BCOR 重组肉瘤。因此，我们对该病例的临床资料进行了回顾性分析，并查阅了有关 ELS 和 BCOR 重组肉瘤的相关文献。本文旨在为BCOR重排埃文样肉瘤患儿的临床特征提供新的见解，并提高对该疾病的认识。
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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