Lovenox Induced Tissue Necrosis, a Case Report and Literature Review

Abdelfatah Abou Issa MD , Richard Simman MD, FACS, FACCWS
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引用次数: 6

Abstract

Lovenox is a trade name for Enoxaparin. It is a low molecular weight heparin (LMWH) and has other trade names like Clexane and Xaparin. It is an anticoagulant used to prevent and treat venous thromboembolism events (VTE) like deep vein thrombosis or pulmonary embolism, and is given as a subcutaneous injection. General speaking, the most common skin reactions as a result of enoxaparin use are: urticarial, ecchymosis, and even skin necrosis due to vasculitis. These side effects are usually located at the injection site. New studies have pointed out the side effect that could occur a distance from the site of Lovenox injection. In our case extensive skin and subcutaneous tissue necrosis developed at the abdominal wall injection site.

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Lovenox致组织坏死1例报告及文献复习
Lovenox是依诺肝素的商品名。它是一种低分子量肝素(LMWH),还有其他商品名,如Clexane和Xaparin。它是一种抗凝剂,用于预防和治疗静脉血栓栓塞事件(VTE),如深静脉血栓形成或肺栓塞,并作为皮下注射。一般来说,使用依诺肝素最常见的皮肤反应是:荨麻疹、瘀斑,甚至血管炎引起的皮肤坏死。这些副作用通常发生在注射部位。新的研究指出,副作用可能发生在注射Lovenox的地方很远的地方。在我们的病例中,腹壁注射部位出现广泛的皮肤和皮下组织坏死。
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