Metabolomics of Salivary Biomarkers in Yusho Patients.

Goro Kawasaki, Yoko Ichikawa, Izumi Yoshitomi, Masahiro Umeda
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Abstract

Yusho patients had many symptoms, and mouth dryness was one of the important oral symptoms. Presently, some Yusho patients complain of mouth dryness. In the present study, we measured mouth dryness by using an oral moisture checking device and examined metabolites of saliva by using metabolome analysis. We found no difference between Yusho patients and controls in terms of mouth dryness. Concerning metabolomes of saliva, there were some metabolites in Yusho patients that were not in controls.

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玉树患者唾液生物标志物代谢组学研究
玉松患者有多种症状,口干是重要的口腔症状之一。目前,一些玉树病人抱怨口干舌燥。在本研究中,我们使用口腔水分检测装置测量口腔干燥度,并使用代谢组学分析检测唾液的代谢物。我们发现玉树病人和对照组在口腔干燥方面没有区别。在唾液代谢组中,有一些代谢产物在玉树患者中没有出现。
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